Results 1 to 10 of about 852,565 (153)
Strongly correlated and topological states in [111] grown transition metal oxide thin films and heterostructures [PDF]
We highlight recent advances in the theory, materials fabrication, and experimental characterization of strongly correlated and topological states in [111] oriented transition metal oxide thin films and heterostructures, which are notoriously difficult ...
Jak Chakhalian +2 more
doaj +4 more sources
Roles of non-receptor tyrosine kinases in pathogenesis and treatment of depression [PDF]
Major depressive disorder is a chronic psychiatric disease with a high prevalence. Brain mechanisms for depression at cellular and molecular levels are far from clear. Increasing evidence from clinical and preclinical studies reveals critical roles of
John Q. Wang +4 more
doaj +1 more source
Several Janus kinase (JAK) inhibitors (jakinibs) have recently been approved to treat inflammatory, autoimmune and hematological conditions. Despite emerging roles for JAKs and downstream signal transducer and activator of transcription (STAT) proteins ...
Iván Parra-Izquierdo +9 more
doaj +1 more source
Platelet transfusion refractoriness (PTR) is an intractable issue in hematological patients, which increases bleeding risks and hospitalization costs to a great extent.
Xiaofei Song +6 more
doaj +1 more source
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy
Introduction Diabetic nephropathy (DN) is a leading cause of kidney failure. Lysozyme (LYZ) is an essential component of innate immunity and exhibits antibacterial properties.
Yan Ren +4 more
doaj +1 more source
Objective To investigate the effects of β-estradiol (E2) on the phosphorylation of JAK/STAT, PI3K/AKT signaling pathways and the expression of IL-17A in mouse spleen mononuclear cells treated with IL-36β. Methods The spleens were isolated from female SPF
Shuang LIU +7 more
doaj +1 more source
The world seems more burdened with large-scale global problems than ever before. One such challenge is to reverse the growing incidence of mental health issues, particularly in our cities.
Jak Spencer
doaj +9 more sources
JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana +5 more
core +2 more sources
Non-commutative deformation of Chern-Simons theory [PDF]
The problem of the consistent definition of gauge theories living on the non-commutative (NC) spaces with a non-constant NC parameter $\Theta(x)$ is discussed.
Kupriyanov, Vladislav G.
core +3 more sources
Runx1 promotes the development of glioma cells by regulating JAK-STAT signalling pathway
Introduction Human glioma is known as the most frequent and primary malignant tumour of the central nervous system with high aggression and poor prognosis.
Yong Zhang, Qiming Xia, Jun Lin
doaj +1 more source

