Results 41 to 50 of about 391,698 (301)

Statul – persoană juridică de drept public [PDF]

open access: yesRevista Institutului Naţional de Justiţie
Statul, ca persoană juridică de drept public, este subiectul central al raporturilor juridice ce vizează organizarea și funcţionarea puterii în societate.
Preţivatîi Ghenadie
doaj   +1 more source

Caracterizarea comunităților algale ale lacului Rîșcani (or.Chișinău) prin prisma relațiilor interspecifice

open access: yesActa et Commentationes: Ştiinţe Exacte şi ale Naturii, 2021
În cadrul comunităților algale acționează un șir de factori atât biotici, cât și abiotici. Indivizii unei populaţii, prin elaborare de diverse substanţe biologice, acţionează benefic sau dăunător faţă de indivizii altor populaţii de alge.
Boris Nedbaliuc   +6 more
doaj   +1 more source

JAK-STAT and bone metabolism

open access: yes, 2013
Emerging evidences suggest Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway plays an important role in bone development and metabolism.
Li, Jiliang
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

L. longipalpis Jak-STAT-related multiple alignment and phylogenetic trees

open access: yes, 2021
L. longipalpis Jak-STAT-related multiple alignment files generated in MUSCLE multiple sequence alignment built in Geneious 7.1.9 software (Biomatters, New Zealand). Phylogenetic trees were created using MEGA-X software, with the Maximum Likelihood method
Bruno Tinoco-Nunes (11633425)   +6 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Tuberaleyrodes actinodaphnis Takahashi Stat., Stat.

open access: yes, 2018
Published as part of Dubey, Anil Kumar & Martin, Jon H., 2018, A review of the genus Tuberaleyrodes Takahashi (Hemiptera: Aleyrodidae) with description of five new species from Brunei, Hong Kong and Malaysia, pp. 251-282 in Zootaxa 4402 (2) on pages 253-255, DOI: 10.11646/zootaxa.4402.2.2, http://zenodo.org/record ...
Dubey, Anil Kumar, Martin, Jon H.
openaire   +2 more sources

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