Results 41 to 50 of about 1,654,341 (292)
Improved Measurements of Branching Fractions and CP Asymmetries in B-> eta h Decays
We report improved measurements of B decays with an eta meson in the final state using 492 fb^{-1} of data collected by the Belle detector at the KEKB e^+ e^- collider.
Abe, K. +144 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The Role Of The Receptive Field Structure In Neuronal Compressive Sensing Signal Processing [PDF]
The receptive field structure ubiquitous in the visual system is believed to play a crucial role in encoding stimulus characteristics, such as contrast and spectral composition.
Barranca, Victor J. +1 more
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
COMPORTAREA NICHELULUI ÎN ANTIMONIDUL DE GALIU CA DOPANT
În lucrare se analizează particularitățile proprietăților fizice ale antimonidului de galiu dopat cu nichel pentru un diapazon vast de concentrații, până la 3% atomare și temperaturi (2÷300)K. Din analiza în ansamblu a efectelor galvanomagnetice, optice
Andrian GHEORGHIŢĂ +6 more
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
High statistic measurement of the K- -> pi0 e- nu decay form-factors
The decay K- -> pi0 e- nu is studied using in-flight decays detected with the ISTRA+ spectrometer. About 920K events are collected for the analysis. The lambda+ slope parameter of the decay form-factor f+(t) in the linear approximation (average slope) is
A.P. Filin +33 more
core +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source

