Results 71 to 80 of about 1,741,412 (341)

Strange particle production in proton-proton collisions at $\sqrt{s}=0.9$ TeV with ALICE at the LHC [PDF]

open access: yes, 2010
The production of mesons containing strange quarks (K$^0_s$, $\phi$) and both singly and doubly strange baryons ($\Lambda$, Anti-$\Lambda$, and $\Xi$+Anti-$\Xi$) are measured at central rapidity in pp collisions at $\sqrt{s}$ = 0.9 TeV with the ALICE ...
16   +1051 more
core   +9 more sources

JAK-STAT Pathway Inhibition and their Implications in COVID-19 Therapy

open access: yesPostgraduate medicine, 2020
As the incidence of COVID-19 increases with time, more and more efforts are made to pave a way out for the therapeutic strategies to deal with the disease progression.
Sairaj Satarker   +5 more
semanticscholar   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

The Role Of The Receptive Field Structure In Neuronal Compressive Sensing Signal Processing [PDF]

open access: yes, 2017
The receptive field structure ubiquitous in the visual system is believed to play a crucial role in encoding stimulus characteristics, such as contrast and spectral composition.
Barranca, Victor J.   +1 more
core   +1 more source

Measurement of the cross-section and forward-backward charge asymmetry for the b and c-quark in e+e- annihilation with inclusive muons at sqrt(s) = 58 GeV

open access: yes, 2000
We have studied inclusive muon events using all the data collected by the TOPAZ detector at sqrt(s)=58 GeV with an integrated luminosity of 273pb-1. From 1328 inclusive muon events, we measured the ratio R_qq of the cross section for qq-bar production to
A. Miyamoto   +63 more
core   +1 more source

Measurements of Branching Fractions and CP Asymmetries in B-> etah Decays [PDF]

open access: yes, 2004
We report measurements of B to pseudoscalar-pseudoscalar decays with at least one eta meson in the final state using 140 fb^{-1} of data collected by the Belle detector at KEKB e^+ e^- collider. We observe the decay B^+-> eta pi^+ and find evidence of B^+
Abe, K.   +157 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller   +6 more
wiley   +1 more source

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