Results 91 to 100 of about 253,375 (253)
PROPRIETĂŢILE TERAPEUTICE ALE PRODUSELOR APICOLE
Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2018 Produsele apicole reprezintă o sursă bogată de calorii şi o excelentă sursă de substanţe nutritive, conţinând o bogată varietate de vitamine. De asemenea, asigură sau completează mecanisme care se desfăşoară în mod natural într-un organism.
Aurelia CRIVOI +5 more
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TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
Advanced Science, EarlyView.A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2017 Diabetul zaharat apare din cauza producţei insuficiente de insulină de către pancreas; astfel, nivelul glucozei din sânge depăşeşte valorile normale. Statisticile arată o creștere permanentă a cazurilor de diabet zaharat. Circa 5% din populație (cu unele
Iurie BACALOV +5 more
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Advanced Science, EarlyView.SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang +18 more
wiley +1 more source
Advanced Science, EarlyView.This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang +5 more
wiley +1 more source
Advanced Science, EarlyView.AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan +13 more
wiley +1 more source
Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2020 Actuаlmente, diabetul zaharat este cea mai frecventă boală endocrină și este caracterizat prin complicații care se dezvoltă în timp și afectează diverse organe şi sisteme de organe.
Adriana DRUŢĂ +4 more
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Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia
Advanced Science, EarlyView.The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian +12 more
wiley +1 more source
Advanced Science, EarlyView.In GdMn2O5, sublattice‐resolved EXAFS and diffraction analysis reveal pronounced spin‐phonon coupling and an unexpected opposing pressure response: the Mn‐driven Néel temperature slightly decreases while the Gd‐sublattice ordering temperature rises under pressures up to 0.86 GPa.
Romualdo S. Silva Jr. +9 more
wiley +1 more source