Results 191 to 200 of about 112,289 (303)

STAT1 signaling controls cholesterol metabolism in epithelial cells and RSV-induced syncytia formation. [PDF]

Npj Viruses
Agac A, Ludlow M, Knittler MC, Osterhaus ADME, Rimmelzwaan GF, Meineke R.   +5 more
europepmc   +1 more source

Expanding the Fish‐Brain Invitrome With the Senegalese Sole SsB‐1 Cell Line—A Versatile Model for Neurotropic Virus Research

Journal of Fish Diseases, EarlyView.
ABSTRACT Cell lines are essential tools for studying animal physiology and immunopathology, reducing the use of live animals and supporting the 3Rs principle of reduction, refinement, and replacement. The Senegalese sole (Solea senegalensis), a relevant species for Spanish aquaculture diversification, lacks established in vitro models. We developed SsB‐
Yulema Valero, Alberto Cuesta
wiley   +1 more source

Macrophage PRMT9 Ameliorates Acute Myocardial Infarction by Promoting Symmetric Dimethylation and Degradation of STAT1. [PDF]

Circulation
Bai X, Ren R, Yuan J, Yu L, Dong N, Cao N, Zhou M, Zhang J, Li X, He Z, Liu B, Zhang M, Gao C.   +12 more
europepmc   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

A STAT1-Knockout Mouse Model for Chapare Virus Infection and Pathogenesis. [PDF]

Viruses
Monticelli SR, Kuehne AI, Batchelor TG, Richardson JB, Lapoint Z, Williams JL, Coyne SR, Raymond JLW, Zeng X, Stefan CP, Koehler JW, Kugelman JR, Herbert AS.   +12 more
europepmc   +1 more source

A posttranslational proteomic survey of a single anatomically preserved human 20‐week postconception brain

Journal of Anatomy, EarlyView.
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera, H. Bogetofte, P. Jensen, R. Hussain, S. A. Nischal, L. Rihova, G. J. Clowry, M. R. Larsen, Z. Molnár, B. C. Carlyle   +9 more
wiley   +1 more source

ALKBH3 suppresses ischemia/reperfusion-induced PANoptosis by regulating the ZBED6/STAT1/AIM2 axis through m¹A demethylation. [PDF]

Clin Transl Med
Diao H, Wang C, Xiong Y, Zhao Q, Zhang X, Qi X, Zou Y, Li J, Zeng L, Si W, Zhang F, Pang P, Wang N, Bian Y, Yang B.   +14 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

The JAK1-STAT1 signaling pathway triggers inflammation responses in chronic obstructive sleep apnea rat model. [PDF]

PLoS One
Yang L, He J.
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source