Results 81 to 90 of about 29,169,368 (250)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Budget plan SC State University Fiscal Year 2012-13
South Carolina State University submitted to the South Carolina Budget and Control Board, Office of State Budget an annual budget plan with summary of agency's request, program revision request, capital or non-recurring requests, and/or proviso revision ...
South Carolina Budget and Control Board, Office of State Budget
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A review of research in the Oregon State Board of Control, 1962-1966
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from cover.Discusses the origins and scope of the ...
core
Agency activity inventory - Budget & Control Board - Auditor FY 2009-10
The South Carolina Budget and Control Board, Office of State Budget in conjunction with the Office of the Governor published an activity inventory for each agency to assist in the creation of the Executive Budget. The appropriations of the South Carolina
South Carolina Budget and Control Board, Office of State Budget
core +1 more source
An Offline Formulation of MPC for LPV Systems Using Linear Matrix Inequalities
An offline model predictive control (MPC) algorithm for linear parameter varying (LPV) systems is presented. The main contribution is to develop an offline MPC algorithm for LPV systems that can deal with both time-varying scheduling parameter and ...
P. Bumroongsri
doaj +1 more source
In recent years, an automatic collision avoidance system has been put into practical use by various automotive companies. In this study, we propose an automatic collision avoidance system for a four-wheel independent drive vehicle using the state ...
Naoto YOSHIDA +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

