Results 101 to 110 of about 2,446,518 (308)
Frontiers in PhysiologyIntroductionColorectal cancer (CRC) diagnosis from whole-slide histopathology images remains challenging due to pronounced tissue heterogeneity, multi-scale morphological variations, and the subtle nature of early neoplastic changes.
Lei Chen +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Interactive and common knowledge in the state-space model [PDF]
This paper deals with the prevailing formal model for knowledge in contemporary economics, namely the state-space model introduced by Robert Aumann in 1976.
Moscati Ivan
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Data Science in ScienceWe argue for the usage of dynamic linear models (DLMs) for pre-processing and modeling of wastewater data used for surveillance of population infectious disease levels.
Difan Ouyang +4 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Fitting State Space Models with EViews
This paper demonstrates how state space models can be fitted in EViews. We first briefly introduce EViews as an econometric software package. Next we fit a local level model to the Nile data.
Filip A. M. Van den Bossche
core
Efficient Likelihood Evaluation of State-Space Representations [PDF]
We develop a numerical procedure that facilitates efficient likelihood evaluation in applications involving non-linear and non-Gaussian state-space models.
David N. DeJong +4 more
core
Identification of nonlinear lateral flow immunoassay state-space models via particle filter approach
, 2012 This is the post-print of the Article. The official published version can be accessed from the link below - Copyright @ 2012 IEEEIn this paper, the particle filtering approach is used, together with the kernel smoothing method, to identify the state ...
Zidong Wang +9 more
core +1 more source
Data Science in ScienceWastewater surveillance has proven to be a cost-effective cornerstone in public health, offering vital insights into a spectrum of community health issues, particularly during the COVID-19 pandemic.
Katherine B. Ensor +6 more
doaj +1 more source