Results 51 to 60 of about 33,037,406 (304)

Bidirectional Mamba state-space model for anomalous diffusion

JPhys Photonics
Characterizing anomalous diffusion (AnDi) is crucial in order to understand the evolution of complex stochastic systems, from molecular interactions to cellular dynamics. Here, we evaluate the performances regarding such a task of Bi-Mamba, a novel state-
Maxime Lavaud, Yosef Shokeeb, Juliette Lacherez, Yacine Amarouchene, Thomas Salez   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Bootstrap prediction intervals in state-space models [PDF]

, 2008
Prediction intervals in state-space models can be obtained by assuming Gaussian innovations and using the prediction equations of the Kalman filter, with the true parameters substituted by consistent estimates. This approach has two limitations.
Ruiz Ortega, Esther, Ro Rodriguez, Esther Ruiz, Rodríguez, Alejandro, Ruiz, Esther, Alejandro Rodriguez   +5 more
core   +2 more sources

Analysis of DC voltage oscillation mechanism in AC/DC hybrid distribution system

The Journal of Engineering, 2019
DC voltage oscillation occurs more and more frequently in voltage source converter (VSC)-based AC/DC hybrid distribution system (AC/DC HDS). However, currently, the explanation of the oscillation mechanism is not clear enough.
Luyang Li, Wei Pei, Hao Xiao, Wei Deng, Li Kong   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Assessing performance of Bayesian state-space models fit to Argos Satellite telemetry locations processed with Kalman Filtering [PDF]

, 2014
Argos recently implemented a new algorithm to calculate locations of satellite-tracked animals that uses a Kalman filter (KF). The KF algorithm is reported to increase the number and accuracy of estimated positions over the traditional Least Squares (LS)
Silva, Monica A., Ian Jonsen, Thompson Dave, Prieto Rui, Mónica A Silva, Ian Jonsen (468324), Jonsen, Ian, Deborah J F Russell, Silva Mónica A., Rui Prieto (468323), Thompson, David, Prieto, Rui, Russell, Deborah Jill Fraser, Rui Prieto, Thompson, Dave, Jonsen Ian, Mark F Baumgartner, Deborah J. F. Russell (540355), Russell Deborah J. F., Dave Thompson, Russell, Deborah J. F., Dave Thompson (292267), Mark F. Baumgartner (468325), Baumgartner Mark F., Baumgartner, Mark F., Mónica A. Silva (468322)   +25 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Deep State Space Model for Rainfall‐Runoff Simulations

Water Resources Research
The classical way of studying the rainfall‐runoff processes in the water cycle relies on conceptual or physically‐based hydrologic models. Deep learning (DL) has recently emerged as an alternative and blossomed in the hydrology community for rainfall ...
Yihan Wang, Lujun Zhang, Annan Yu, N. Benjamin Erichson, Tiantian Yang   +4 more
doaj   +1 more source