Results 61 to 70 of about 2,446,518 (308)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Second-Order Extended State-Space Model of Switching Converters

CSEE Journal of Power and Energy Systems
The state space average model of switching converters transforms time varying differential equations into time invariant differential equations by the averaging method in math.
Renji Huang, Fan Ma, Gang Wang, Runlong Xiao   +3 more
doaj   +1 more source

A Time-Efficient Approach for Modelling and Simulation of Aggregated Multiple Photovoltaic Microinverters

Energies, 2017
This paper presents a time-efficient modeling and simulation strategy for aggregated microinverters in large-scale photovoltaic systems. As photovoltaic microinverter systems are typically comprised of multiple power electronic converters, a suitable ...
Sungmin Park, Weiqiang Chen, Ali M. Bazzi, Sung-Yeul Park   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Bootstrap prediction intervals in state-space models [PDF]

, 2008
Prediction intervals in state-space models can be obtained by assuming Gaussian innovations and using the prediction equations of the Kalman filter, with the true parameters substituted by consistent estimates. This approach has two limitations.
Ruiz Ortega, Esther, Ro Rodriguez, Esther Ruiz, Rodríguez, Alejandro, Ruiz, Esther, Alejandro Rodriguez   +5 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Online State Space Model Parameter Estimation in Synchronous Machines

Iranian Journal of Electrical and Electronic Engineering, 2014
The purpose of this paper is to present a new approach based on the Least Squares Error method for estimating the unknown parameters of the nonlinear 3rd order synchronous generator model.
Z. Gallehdari, M. Dehghani, K. Nikravesh
doaj  

Stability Analysis in Multi-VSC (Voltage Source Converter) Systems of Wind Turbines

Applied Sciences
In this paper, a holistic nonlinear state-space model of a system with multiple converters is developed, where the converters correspond to the wind turbines in a wind farm and are equipped with grid-following control.
Dimitrios Dimitropoulos, Xiongfei Wang, Frede Blaabjerg   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source