Results 91 to 100 of about 948,220 (309)

Proximal-type epithelioid sarcoma of the vulva initially misdiagnosed as Bartholin cyst: A case report

Gynecology and Obstetrics Clinical Medicine, 2022
Rafael Everton Assunção Ribeiro da Costa, Luis Felipe Rodrigues Brandão de Barros, Raimundo Gerônimo da Silva Júnior, Eugênio de Sá Coutinho Neto, Eid Gonçalves Coelho, Carlos Eduardo Coelho de Sá   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Circuit complexity and entanglement in many-body quantum systems [PDF]

, 2021
Entanglement and circuit complexity are fundamental concepts in quantum information theory which turned out to have considerable applications in various contexts ranging from many-body systems and condensed matter theory to quantum gravity and black hole
Di Giulio, Giuseppe
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

State Complexity of Multiple Concatenation

CoRR
We describe witness languages meeting the upper bound on the state complexity of the multiple concatenation of $k$ regular languages over an alphabet of size $k+1$ with a significantly simpler proof than that in the literature. We also consider the case where some languages may be recognized by two-state automata.
Jozef Jirásek 0001, Galina Jirásková
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Krylov complexity of thermal state in early universe

European Physical Journal C: Particles and Fields
Thermal interactions are ubiquitous in the cosmos, driving systems toward equilibrium. In this work, we investigate the evolution of thermal states across the early universe, encompassing the inflationary, radiation-dominated (RD), and matter-dominated ...
Tao Li, Lei-Hua Liu
doaj   +1 more source

Dynamic reward-penalty incentives and occupational health governance: an evolutionary game analysis with public health implications

Frontiers in Public Health
IntroductionOccupational health risks remain a significant public health concern in environmentally intensive industries, where inadequate regulatory enforcement and weak enterprise compliance can result in persistent workplace health hazards and ...
Yanan Li, Debin Fang, Debin Fang, Debin Fang, Tong Lou, Luping Jiang   +5 more
doaj   +1 more source

Visualizing Quantum Circuit Probability: Estimating Quantum State Complexity for Quantum Program Synthesis. [PDF]

Entropy (Basel), 2023
Bach BG, Kundu A, Acharya T, Sarkar A.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source