Results 71 to 80 of about 948,220 (309)
, 2020 Despite considerable appeal, the growing appreciation of biosignals complexity reflects that system complexity needs additional support. A dynamically coordinated network of neurovisceral integration has been described that links prefrontal-subcortical ...
Beatrice Spiluttini +4 more
core +1 more source
Reinforcement Learning With Low-Complexity Liquid State Machines
Frontiers in Neuroscience, 2019 We propose reinforcement learning on simple networks consisting of random connections of spiking neurons (both recurrent and feed-forward) that can learn complex tasks with very little trainable parameters.
Wachirawit Ponghiran +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Complexity and state-transitions in social dependence networks
Discrete Dynamics in Nature and Society, 2001 Computation of complexity in Social Dependence Networks is an interesting research domain to understand evolution processes and group exchange dynamics in natural and artificial intelligent Multi-Agent Systems.
Giuliano Pistolesi, Pierluigi Modesti
doaj +1 more source
Advances in applied ecological models for estuarine management
Shui kexue jinzhan, 2015 Estuaries are transitional water zones as functional ecotones connecting rivers and oceans. Both of natural forces and human activities drive estuarine ecosystems variations. Ecological modeling plays a significant role in studying structure and function
SHEN Xia, B.Larry LI
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Operational state complexity under Parikh equivalence
, 2014 We investigate, under Parikh equivalence, the state complexity of some language operations which preserve regularity. For union, concatenation, Kleene star, complement, intersection, shuffle, and reversal, we obtain a polynomial state complexity over any
G.J. Lavado, G. Pighizzini, S. Seki
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source