Results 121 to 130 of about 29,875,727 (301)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Long History of “Doublethink”: A Response to Djelal Kadir’s “Agnotology and the Know-Nothing Party: Then and Now”

open access: yesReview of International American Studies, 2017
Manuel Broncano Rodríguez Texas A&M International University  The Long History of “Doublethink”: A Response to Djelal Kadir’s “Agnotology and the Know-Nothing Party: Then and Now” A Response to Djelal Kadir’s “Agnotology and the Know-Nothing Party ...
Manuel Broncano Rodríguez
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Bifurcation Oscillator as an Advanced Sensor for Quantum State Control. [PDF]

open access: yesSensors (Basel), 2022
Pashin D   +3 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Agency activity inventory Budget & Control Board

open access: yes, 2009
The South Carolina Budget and Control Board, Office of State Budget in conjunction with the Office of the Governor published an activity inventory for each agency to assist in the creation of the Executive Budget. The appropriations of the South Carolina
South Carolina Budget and Control Board, Office of State Budget
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Agency budget plan SC Office of the State Treasurer Fiscal Year 2014-15

open access: yes, 2013
The South Carolina Office of the State Treasurer submitted to the South Carolina Budget and Control Board, Office of State Budget an annual budget plan with summary of agency's request, program revision request, capital or non-recurring requests, and/or ...
South Carolina Budget and Control Board, Office of State Budget
core   +1 more source

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