Results 141 to 150 of about 4,095,936 (316)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Agency activity inventory - Secretary of State FY 2009-10

open access: yes, 2009
The South Carolina Budget and Control Board, Office of State Budget in conjunction with the Office of the Governor published an activity inventory for each agency to assist in the creation of the Executive Budget. The appropriations of the South Carolina
South Carolina Budget and Control Board, Office of State Budget
core  

STATE BUDGET AND CONTROL BOARD [PDF]

open access: yes, 1999
Each year the South Carolina Budget and Control Board produces an annual accountability report for the South Carolina General Assembly. Included is a discussion and analysis, major achievements for the year, arts development and goals for the ...
South Carolina Budget and Control Board
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Photochemical spin-state control of binding configuration for tailoring organic color center emission in carbon nanotubes. [PDF]

open access: yesNat Commun, 2022
Zheng Y   +10 more
europepmc   +1 more source

Agency budget plan South Carolina State Board for Technical and Comprehensive Education Fiscal Year 2014-15

open access: yes, 2013
The South Carolina State Board for Technical and Comprehensive Education submitted to the South Carolina Budget and Control Board, Office of State Budget an annual budget plan with summary of agency's request, program revision request, capital or non ...
South Carolina Budget and Control Board, Office of State Budget
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Gambling harms caused by electronic gambling machines should be prevented with state control. [PDF]

open access: yesNordisk Alkohol Nark, 2021
Järvinen-Tassopoulos J   +2 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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