Results 131 to 140 of about 29,875,727 (301)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

State Compensation Linearization and Control

open access: yesCoRR
The linearization method builds a bridge from mature methods for linear systems to nonlinear systems and has been widely used in various areas. There are currently two main linearization methods: Jacobian linearization and feedback linearization.
Quan Quan, Jinrui Ren
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Agency activity inventory - South Carolina State University FY 2009-10

open access: yes, 2009
The South Carolina Budget and Control Board, Office of State Budget in conjunction with the Office of the Governor published an activity inventory for each agency to assist in the creation of the Executive Budget.
South Carolina Budget and Control Board, Office of State Budget
core   +1 more source

Is port state control influenced by the COVID-19? Evidence from inspection data. [PDF]

open access: yesTransp Policy (Oxf), 2022
Yan R, Mo H, Guo X, Yang Y, Wang S.
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Agency budget plan Office of the State Auditor Fiscal Year 2014-15

open access: yes, 2014
The South Carolina Office of the State Auditor submitted to the South Carolina Budget and Control Board, Office of State Budget an annual budget plan with summary of agency's request, program revision request, capital or non-recurring requests, and/or ...
South Carolina Budget and Control Board, Office of State Budget
core   +1 more source

Agency activity inventory - Budget & Control Board - Auditor FY 2009-10

open access: yes, 2009
The South Carolina Budget and Control Board, Office of State Budget in conjunction with the Office of the Governor published an activity inventory for each agency to assist in the creation of the Executive Budget. The appropriations of the South Carolina
South Carolina Budget and Control Board, Office of State Budget
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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