Results 271 to 280 of about 33,846,845 (391)
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Thalamic state control of cortical paired-pulse dynamics.
J Neurophysiol, 2017 Whitmire CJ, Millard DC, Stanley GB.
europepmc +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The Optimal Control Method of Transmission Line Fittings Limits in Low Power Consumption State [PDF]
Chaojun Qian, Fan Zhang, Long Zhang
openalex +1 more source
State Control and the Effects of Foreign Relations on Bilateral Trade
, 2014 Christina L. Davis +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A solid-state control system for dynein-based ciliary/flagellar motility. [PDF]
J Cell Biol, 2013 King SM.
europepmc +1 more source