Results 41 to 50 of about 19,255,488 (244)
Resumen: Estudio de la regulación constitucional y normativa del Consejo de Estado español, desde su reconocimiento constitucional en 1978, pasando por la ley orgánica 3/1980, hasta la reforma acaecida por ley orgánica 3/2004, en los ámbitos referidos a ...
José Manuel Vera Santos
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Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Other title: SRC annual report; Other title: State Rehabilitation Council annual report
Annual; Report year ends Sept. 30.; Issued by: State Rehabilitation Advisory Council, -2000/2001; by the State Rehabilitation Council, 2001 ...
Connecticut. State Rehabilitation Council.
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Prevention and control measures to further optimize COVID‐19 response
On November 11, 2022, the Chinese government released the Scientific and Targeted Prevention and Control Measures to Optimize COVID‐19 Response. Since that time, adjusted measures have been implemented throughout China, leading to major shifts in ...
Released by the Taskforce for Joint Prevention and Control Mechanism for COVID‐19 under the State Council of P.R. China on December 07, 2022
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Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Other title: SRC annual report; Other title: State Rehabilitation Council annual report
Annual; Report year ends Sept. 30.; Issued by: State Rehabilitation Advisory Council, -2000/2001; by the State Rehabilitation Council, 2001 ...
Connecticut. State Rehabilitation Council.
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Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
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A PROPOSAL TO ESTABLISH A COUNCIL OF STATE IN POLAND Summary In 2006 Janusz Kochanowski, Poland’s Civil Rights Spokesman, put forward a proposal for the establishment of a council of state.
Marek Krzymkowski
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