Results 101 to 110 of about 2,813,920 (263)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Approximate power flow solutions‐based forecasting‐aided state estimation for power distribution networks

IET Generation, Transmission & Distribution
This paper presents an approximate power flow model‐based forecasting‐aided state estimation estimator for power distribution networks subject to naive forecasting methods and nonlinear filtering processes.
Zhenyu Wang, Zhao Xu, Donglian Qi, Yunfeng Yan, Jianliang Zhang   +4 more
doaj   +1 more source

A Moving Target Defense Strategy against Load Redistribution Attacks

Zhongguo dianli
The load redistribution attack considers the actual equipment configuration and operation of the power system, and poses a threat to the safe and stable operation of the power system by tampering with load measurements.
Quanpeng HE, Wei LIU, Weiyong YANG, Xingshen WEI, Qi WANG   +4 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Optimizing decentralized implementation of state estimation in active distribution networks

IET Generation, Transmission & Distribution
The challenges facing active distribution networks have highlighted the position of the distribution system state estimation (DSSE) process in the distribution management systems as its most important function.
Mohammad Gholami, Aref Eskandari, Sajjad Fattaheian‐Dehkordi, Matti Lehtonen   +3 more
doaj   +1 more source

Key Technology and Development Prospect of Ontology Safety for Lithium-Ion Battery Storage Power Stations

Zhongguo dianli
The introduction of the "dual carbon" targets and the ongoing advancement of low-carbon transitions in energy and electricity have posed significant challenges to the new-type power system, which primarily relies on renewable energy sources, particularly
Xiangyang XIA, Xinxin TAN, Zhouping SHAN, Hui LI, Zhiqiang XU, Jinbo WU, Jiahui YUE, Guiquan CHEN   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Linear Matrix Inequalities in Fault Detection Filter Design for Linear Ostensible Metzler Systems

Machines
The article deals with the properties of fault detection filters when applying their structure to a class of linear, continuous-time systems, with dynamics being specified by the system matrix of the ostensible Metzler structure. The proposed solution is
Dušan Krokavec, Anna Filasová
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source