Results 131 to 140 of about 771,552 (305)
application/pdfIn the present paper, the general recursive parameter estimation problem of identifying the unknown parameters subject to the sequential observation is studied from the information theoretic view point.
ニキホルク, ピータ +3 more
core
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
This paper investigates the joint state and parameter estimation issue of the bilinear state–space system with non-Gaussian process noise and non-Gaussian measurement noise.
Xuehai Wang, Yijuan Duan
doaj +1 more source
State estimation of wastewater treatment processes using distributed extended Kalman filters
In this work, we develop a distributed state estimation scheme for wastewater treatment processes in the context of extended Kalman filtering. Specifically, we consider a wastewater treatment process that includes a five-compartment reactor and an ideal ...
Zeng, Jing +3 more
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Nonlinear MPC With Enhanced State Estimation Using UKF for Interacting Variable Area Hybrid Process
Most of the process industries use variable area tank processes such as conical and spherical tank processes. However, their nonlinear dynamics and interactions between such processes along with measurement noise, make controller design challenging.
Sathish Kumar Samy +3 more
doaj +1 more source
This is the post-print version of the Article. The official published version can be accessed from the links below - Copyright @ 2012 ACM.This article is concerned with a new distributed state estimation problem for a class of dynamical systems in sensor
Liu, X, Liang, J, Wang, Z, Shen, B
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Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

