Results 11 to 20 of about 15,785 (210)

Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair

Nature Communications, 2022
G2/M arrest of epithelial cells leads to fibrosis with unclear mechanisms. This study identifies a protein-encoding circRNA, circBNC2, which inhibits epithelial cells G2/M arrest to prevent fibrotic maladaptive repair in damaged kidney and liver ...
Peng Wang, Zhitao Huang, Yili Peng, Hongwei Li, Tong Lin, Yingyu Zhao, Zheng Hu, Zhanmei Zhou, Weijie Zhou, Youhua Liu, Fan Fan Hou   +10 more
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The emergence of a “City of Cages” in Lima: neighbourhood appropriation in the context of rising insecurities

Cybergeo, 2007
Lima, like other Latin American metropolises, has experienced profound changes in the context of broader transformation processes since the 1990s. Gated residential developments have emerged as one characteristic feature of the new spatial order.
Jörg Plöger
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Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function

Biology, 2023
Both mitochondrial quality control and energy metabolism are critical in maintaining the physiological function of cardiomyocytes. When damaged mitochondria fail to be repaired, cardiomyocytes initiate a process referred to as mitophagy to clear ...
Zhuang Ma, Zuheng Liu, Xudong Li, Hao Zhang, Dunzheng Han, Wenjun Xiong, Haobin Zhou, Xi Yang, Qingchun Zeng, Hao Ren, Dingli Xu   +10 more
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State Failure [PDF]

Annual Review of Political Science, 2008
State failure is characterized by government predation and the militarization of civic society. Drawing on data from the study of civil war, state failure, and violence, this article explores the roles of per capita income, ethnicity, and democratization.
openaire   +1 more source

Failed States Status in Contemporary International Law [PDF]

Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2013
Since the end of the cold war, the International Community has become increasingly preoccupied with a phenomenon giving rise to a wide range of humanitarian, legal and security strains generally known as ‘State failure’.
Aramesh Shahbazi, Khadijeh Javadi Sharif
doaj  

Clinical Profile, Treatment, and Prognosis of Left Ventricular Thrombus in Dilated Cardiomyopathy

Clinical and Applied Thrombosis/Hemostasis, 2023
Despite the emerging prevalence of left ventricular (LV) thrombus in dilated cardiomyopathy (DCM), clinical characteristics, management, and disease prognosis are poorly studied. We aim to assess the efficacy/safety profile of direct oral anticoagulants (
Liyan Huang MM, Xuemei Zhao MD, Jing Wang MM, Lin Liang MD, Pengchao Tian MD, Yuyi Chen MD, Mei Zhai MD, Yan Huang MD, Qiong Zhou MM, Anran Xin MB, Yuhui Zhang MD, PhD, Jian Zhang MD, PhD   +11 more
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State failure and dilemma of security cooperation among neighbouring countries in the Global South: Evidence from Myanmar and Thailand

European Journal of International Security
This paper argues that security cooperation among neighbouring countries in the Global South is often hampered by domestic instability and fragmented territorial control resulting from state failures.
Enze Han, Sirada Khemanitthathai
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Targeted inhibition of PTPN22 is a novel approach to alleviate osteogenic responses in aortic valve interstitial cells and aortic valve lesions in mice

BMC Medicine, 2023
Background Calcific aortic valve disease (CAVD) is the most prevalent valvular disease and has high morbidity and mortality. CAVD is characterized by complex pathophysiological processes, including inflammation-induced osteoblastic differentiation in ...
Shunyi Li, Zichao Luo, Shuwen Su, Liming Wen, Gaopeng Xian, Jing Zhao, Xingbo Xu, Dingli Xu, Qingchun Zeng   +8 more
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Programmable Synthetic Protein Circuits for the Identification and Suppression of Hepatocellular Carcinoma

Molecular Therapy: Oncolytics, 2020
Precisely identifying and killing tumor cells are diligent pursuits in oncotherapy. Synthesized gene circuits have emerged as an intelligent weapon to solve these problems.
Xu Han, Jiong Yang, Fanhong Zeng, Jun Weng, Yue Zhang, Qing Peng, Li Shen, Shigang Ding, Kaiyu Liu, Yi Gao   +9 more
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Identification of Radiotherapy-Associated Genes in Lung Adenocarcinoma by an Integrated Bioinformatics Analysis Approach

Frontiers in Molecular Biosciences, 2021
Radiotherapy (RT) plays an important role in the prognosis of lung adenocarcinoma (LUAD) patients, but the radioresistance (RR) of LUAD is still a challenge that needs to be overcome.
Junhao Wang, Qizheng Han, Huizi Liu, Haihua Luo, Lei Li, Aihua Liu, Yong Jiang   +6 more
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