Results 21 to 30 of about 4,363,521 (251)

State failure and dilemma of security cooperation among neighbouring countries in the Global South: Evidence from Myanmar and Thailand

European Journal of International Security
This paper argues that security cooperation among neighbouring countries in the Global South is often hampered by domestic instability and fragmented territorial control resulting from state failures.
Enze Han, Sirada Khemanitthathai
doaj   +1 more source

Targeted inhibition of PTPN22 is a novel approach to alleviate osteogenic responses in aortic valve interstitial cells and aortic valve lesions in mice

BMC Medicine, 2023
Background Calcific aortic valve disease (CAVD) is the most prevalent valvular disease and has high morbidity and mortality. CAVD is characterized by complex pathophysiological processes, including inflammation-induced osteoblastic differentiation in ...
Shunyi Li, Zichao Luo, Shuwen Su, Liming Wen, Gaopeng Xian, Jing Zhao, Xingbo Xu, Dingli Xu, Qingchun Zeng   +8 more
doaj   +1 more source

Failed States Status in Contemporary International Law [PDF]

Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2013
Since the end of the cold war, the International Community has become increasingly preoccupied with a phenomenon giving rise to a wide range of humanitarian, legal and security strains generally known as ‘State failure’.
Aramesh Shahbazi, Khadijeh Javadi Sharif
doaj  

Gaussian process surrogates for failure detection: a Bayesian experimental design approach

, 2015
An important task of uncertainty quantification is to identify {the probability of} undesired events, in particular, system failures, caused by various sources of uncertainties.
Li, Jinglai, Lin, Guang, Wang, Hongqiao
core   +1 more source

Tekutá teritorialita a hnutí al-Šabáb

Czech Journal of International Relations, 2020
The text presents a contribution to the study of territoriality of violent non-state actors in areas of limited internal state power projection. It presents the strategy of liquid territoriality as a survival strategy of the territorial violent non-state
Doboš, Bohumil
doaj  

Sirt1 Antisense Long Noncoding RNA Promotes Cardiomyocyte Proliferation by Enhancing the Stability of Sirt1

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Antisense long noncoding RNAs (lncRNAs) are single‐stranded RNAs that overlapped gene‐coding regions on the opposite DNA strand and play as critical regulators in cardiovascular diseases.
Bing Li, Yinlan Hu, Xinzhong Li, Guoqing Jin, Xiaoqiang Chen, Guojun Chen, Yanmei Chen, Senlin Huang, Wangjun Liao, Yulin Liao, Zhonghua Teng, Jianping Bin   +11 more
doaj   +1 more source

Programmable Synthetic Protein Circuits for the Identification and Suppression of Hepatocellular Carcinoma

Molecular Therapy: Oncolytics, 2020
Precisely identifying and killing tumor cells are diligent pursuits in oncotherapy. Synthesized gene circuits have emerged as an intelligent weapon to solve these problems.
Xu Han, Jiong Yang, Fanhong Zeng, Jun Weng, Yue Zhang, Qing Peng, Li Shen, Shigang Ding, Kaiyu Liu, Yi Gao   +9 more
doaj   +1 more source

Identification of Radiotherapy-Associated Genes in Lung Adenocarcinoma by an Integrated Bioinformatics Analysis Approach

Frontiers in Molecular Biosciences, 2021
Radiotherapy (RT) plays an important role in the prognosis of lung adenocarcinoma (LUAD) patients, but the radioresistance (RR) of LUAD is still a challenge that needs to be overcome.
Junhao Wang, Qizheng Han, Huizi Liu, Haihua Luo, Lei Li, Aihua Liu, Yong Jiang   +6 more
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Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

The effects of ultrasound exposure on P-glycoprotein-mediated multidrug resistance in vitro and in vivo

Journal of Experimental & Clinical Cancer Research, 2018
Background Multidrug resistance (MDR) is often responsible for the failure of chemotherapy treatment, and current strategies for cancer MDR are not adequately satisfying as to their efficacy and safety.
Chixiong Huang, Senlin Huang, Hairui Li, Xinzhong Li, Bing Li, Lintao Zhong, Junfeng Wang, Meishen Zou, Xiang He, Hao Zheng, Xiaoyun Si, Wangjun Liao, Yulin Liao, Li Yang, Jianping Bin   +14 more
doaj   +1 more source