Results 31 to 40 of about 4,363,521 (251)

Cities and global governance: State failure or a new global order? [PDF]

open access: yes, 2016
International society, so long the resolution to problems of collective political order, now appears to be failing in its capacity to deal with transnational challenges such as climate change, global security and financial instability.
Curtis, Simon
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

The top tertile of hematocrit change during hospitalization is associated with lower risk of mortality in acute heart failure patients

open access: yesBMC Cardiovascular Disorders, 2017
Background Hemoconcentration has been proposed as surrogate for changes in volume status among patients hospitalized with acute heart failure (AHF) and is associated with a favorable outcome.
Haobin Zhou   +6 more
doaj   +1 more source

Extracellular vesicles of Fusobacterium nucleatum compromise intestinal barrier through targeting RIPK1-mediated cell death pathway

open access: yesGut Microbes, 2021
Microbial factors that mediate microbes-host interaction in ulcerative colitis (UC), a chronic disease seriously affecting human health, are not fully known. The emerging oncobacterium Fusobacterium nucleatum (Fn) secretes extracellular vesicles carrying
Le Liu   +4 more
doaj   +1 more source

Testing from a nondeterministic finite state machine using adaptive state counting [PDF]

open access: yes, 2004
The problem of generating a checking experiment from a nondeterministic finite state machine has been represented in terms of state counting. However, test techniques that use state counting traditionally produce preset test suites.
Hierons, RM
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Association between admission plasma 2-oxoglutarate levels and short-term outcomes in patients with acute heart failure: a prospective cohort study

open access: yesMolecular Medicine, 2019
Background 2-oxoglutarate (2OG), an intermediate metabolite in the tricarboxylic acid cycle, has been found to associate with chronic heart failure (HF), but its effect on short-term adverse outcomes in patients with acute HF (AHF) is uncertain.
Zhengliang Peng   +10 more
doaj   +1 more source

Some advances in importance sampling of reliability models based on zero variance approximation [PDF]

open access: yes, 2012
We are interested in estimating, through simulation, the probability of entering a rare failure state before a regeneration state. Since this probability is typically small, we apply importance sampling.
Boer, Pieter-Tjerk de   +3 more
core   +2 more sources

The Haldane bosonisation scheme and metallic states of interacting fermions in d spatial dimensions

open access: yes, 2000
We consider the Haldane bosonisation scheme in d spatial dimensions as applied to a realistic model of interacting fermions in d=2 and unequivocally demonstrate failure of this scheme in d > 1, specifically in d=2.
Farid, Behnam
core   +1 more source

An immunocompromised dialysis patient with skin and bone lesions [PDF]

open access: yes, 2010
Patients with chronic kidney failure have disturbances of immune function involving both innate and adaptive systems. These result in both immunodepression which increases susceptibility to infection and immunoactivation leading to a chronic inflammatory
Brown   +7 more
core   +2 more sources

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