Results 51 to 60 of about 4,363,521 (251)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Associations of habitual glucosamine supplementation with incident gout: a large population based cohort study

open access: yesBiology of Sex Differences, 2022
Highlights 1. Glucosamine use was associated with lower risk of incident gout in females. 2. The inverse association between glucosamine use and gout was stronger in females with diuretics use. 3. Gout genetic risk scores did not significantly modify the
Mengyi Liu   +9 more
doaj   +1 more source

Residential green and blue spaces with nonalcoholic fatty liver disease incidence: Mediating effect of air pollutants

open access: yesEcotoxicology and Environmental Safety, 2023
Background: This study aimed to investigate the relationship of residential green and blue spaces with incident nonalcoholic fatty liver disease (NAFLD), and explore the potential mediation effects of air pollutants and modification effect of genetic ...
Mengyi Liu   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

How Hope Defi(n)es South Africa: Reimagining Hope in Johannesburg’s Slovo Park Beyond State Failures

open access: yesThe February Journal
This article examines the dual role of hope in South Africa, highlighting its power as both a transformative force and a constraining burden amid systemic state failures and persistent socio-economic inequalities.
Eileen Jahn
doaj   +1 more source

Variety and quantity of dietary protein intake from different sources and risk of new-onset diabetes: a Nationwide Cohort Study in China

open access: yesBMC Medicine, 2022
Background The relation of the variety and quantity of different sources of dietary proteins intake and diabetes remains uncertain. We aimed to investigate the associations between the variety and quantity of proteins intake from eight major food sources
Chun Zhou   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Enhancement of reliability in condition monitoring techniques in wind turbines [PDF]

open access: yes, 2019
The majority of electrical failures in wind turbines occur in the semiconductor components (IGBTs) of converters. To increase reliability and decrease the maintenance costs associated with this component, several health-monitoring methods have been ...
Dinh, Truong Quang   +5 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Ising model for distribution networks [PDF]

open access: yes, 2011
An elementary Ising spin model is proposed for demonstrating cascading failures (break-downs, blackouts, collapses, avalanches, ...) that can occur in realistic networks for distribution and delivery by suppliers to consumers. A ferromagnetic Hamiltonian
Aleksiejuk A   +26 more
core   +1 more source

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