Results 51 to 60 of about 11,105,488 (338)

Options of biological substances application in rectal fistulas treatment (Review of the literature)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2016
Aim of review. To present literature data of the treatment of incomplete rectal fistulas with application of biological substances. Summary. Treatment of rectal fistulas remains burning issue in coloproctology due to unsatisfactory results of surgery ...
A. M. Kuzminov, S. A. Frolov, D. V. Vyshegorodtsev, V. Yu. Korolik, Sh. T. Minbayev, I. S. Bogormistrov, M. O. Chernozhukova   +6 more
doaj   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Rethinking State Politics: The Withering of State Dominant Machines in Brazil

Brazilian Political Science Review, 2007
Research on Brazilian federalism and state politics has focused mainly on the impact of federal arrangements on national political systems, whereas comparative analyses of the workings of state political institutions and patterns of political competition
André Borges
doaj  

Diagnosis and treatment of incomplete internal rectal fistulas

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of review. To present literature data on diagnosis and treatment of incomplete internal rectal fistulas. Summary. Incomplete internal rectal fistulas is an insufficiently studied «niche» in proctology.
M. O. Chernozhukova, A. M. Kuzminov, S. A. Frolov, Vyacheslav Yu. Korolik, Sh. T. Minbayev, R. R. Eligulashvili   +5 more
doaj   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

Comparative efficacy of Doppler-guided hemorrhoidal artery ligation with mucopexy and hemorrhoidectomy

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2016
Aim of investigation. To estimate efficacy of Doppler-controlled dearterialization of internal hemorrhoids with mucopexy by instrumental diagnostic tests. Material and methods. Randomized, prospective trial included 240 patients with hemorrhoids of the 3-
A. Yu. Titov, Maryana V. Abritsova, L. P. Orlova, O. Yu. Fomenko, Yu. L. Trubacheva, D. A. Mtvralashvili   +5 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

The first experience of two-stage treatment of transsphincteric fistulas of rectum by means of fibrin sealant

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of investigation. To improve the short­term and long­term results of transsphincteric rectal fistulas treatment by patented two­stage method that includes elimination of fistulous tract with the subsequent enzyme treatment of the wound channel and ...
S. A. Frolov, A. M. Kuzminov, V. Yu. Korolik, I. S. Bogormistrov, M. O. Chernozhukova, Sh. T. Minbayev   +5 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

The clinical role of blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of investigation. To estimate the clinical and prognostic value of carriage of various blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C (CHC).
Yekaterina Ye. Starostina, M. V. Sokolova, L. M. Samokhodskaya, T. П. Rozina, T. N. Krasnova, Ye. B. Yarovaya, N. A. Mukhin   +6 more
doaj   +1 more source