Results 71 to 80 of about 11,105,488 (338)

The Effect of Legalized Gambling on State Government Revenue

open access: yes, 2011
Legalized gambling is an attractive option to state governments facing tightening fiscal constraints. Yet, the empirical evidence on the effect of gambling on state revenues is limited.
Douglas Walker, J. Jackson
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Diagnostics and treatment of Clostridium difficile-associated disease: Guidelines of the Russian gastroenterological association

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of publication. To present with clinical guidelines of the Russian gastroenterological association on Clostridium difficile-associated disease management to practical doctors. Summary. Clostridium difficile-associated disease develops at disorders of
V. T. Ivashkin   +11 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Diagnostics and treatment of peptic ulcer: clinical guidelines of the Russian gastroenterological Association

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
The aim of publication. To present modern concept on etiology and pathogenesis of the peptic ulcer (PUD) to general practitioners, to acquaint them with modern diagnostic methods and main treatment approaches of this disease. Summary.
V. T. Ivashkin   +8 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

The role of polymorphism (rs1800566) of NAD(F)H quinone oxidoreductase-1 in development of acute pancreatitis

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of investigation. To estimate the role of genetic polymorphism (rs1800566) of NAD(F)H quinone oxidoreductase-1 in development of acute pancreatitis in the Russian population. Material and methods.
T. A. Samgina   +4 more
doaj   +1 more source

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