Results 71 to 80 of about 15,527,786 (403)

Functional genre in Illinois State Government digital documents [PDF]

open access: yes, 2010
Provisions for collecting or archiving digital documents can be informed by knowledge of the genres of documents likely to be encountered. Although different aspects of collecting and curation may classify documents into genres based on differing ...
Jackson, Larry S.
core  

Secure SQL Server - Enabling Secure Access to Remote Relational Data [PDF]

open access: yesarXiv, 2012
The Secure SQL Server - SecSS, is a technology primarily developed to enable self-service governance of states, as described in (Paulin 2012). Self-service governance is a novel model of governance that rejects service-based public administration and instead proposes that governed subjects manage their legal relations in a self-service manner, based on
arxiv  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Diagnosis and treatment of incomplete internal rectal fistulas

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of review. To present literature data on diagnosis and treatment of incomplete internal rectal fistulas. Summary. Incomplete internal rectal fistulas is an insufficiently studied «niche» in proctology.
M. O. Chernozhukova   +5 more
doaj   +1 more source

Human Resource Management in New Jersey State Government [PDF]

open access: yes, 2006
In 2005, the State of New Jersey Department of Personnel commissioned the Heldrich Center to study the critical human resource management issues confronting New Jersey state government.
Angie McGuire   +3 more
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Local government financial autonomy in Nigeria: The State Joint Local Government Account

open access: yesCommonwealth Journal of Local Governance, 2010
This paper addresses the statutory financial relations and financial autonomy of local government in Nigeria, and the freedom of local government to generate revenue from its assigned sources without external interference.
Jude Okafor
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

The clinical role of blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of investigation. To estimate the clinical and prognostic value of carriage of various blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C (CHC).
Yekaterina Ye. Starostina   +6 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

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