Results 121 to 130 of about 1,278,837 (306)

Antibiotic use in different hospital administrative categories: an overview of 10 years of a statewide surveillance program in Brazil

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Objective: The present study aimed to describe ICU antibiotic use based on data reported from 2009 to 2018 to the Nosocomial Surveillance System (NSS) of the State Health Department in the State of Sao Paulo, Brazil. Design: Ecological study. Setting:
Filipe Piastrelli   +3 more
doaj   +1 more source

Hospital Employment and Local Unemployment: Evidence from French Health Reforms [PDF]

open access: yes, 2015
We here ask whether French local authorities respond to depressed local labour markets by increasing employment in State-owned hospitals. We use 2006-2010 panel data to examine within-hospital employment changes: higher local unemployment is associated ...
Clark, Andrew E., Milcent, Carine
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The relationship between state-level factors and LGBTQ+ policies in diverse healthcare settings in the United States: a cross-sectional multilevel analysis

open access: yesBMC Health Services Research
Background Lesbian, gay, bisexual, transgender, queer or questioning, and other sexual and gender diverse (LGBTQ+) individuals face persistent discrimination in healthcare settings, highlighting organizational inclusion efforts to reduce these inequities.
Hyunmin Yu   +6 more
doaj   +1 more source

Association of Insurance Mix and Diagnostic Coding Practices in New York State Hospitals.

open access: yesJAMA Health Forum, 2022
Dragan KL   +3 more
europepmc   +1 more source

Questionable care: avoiding ineffective treatment [PDF]

open access: yes
Overview In some hospitals, far too many people get a treatment they should not get, even when the evidence is clear that it is unnecessary or doesn’t work. Australia urgently needs a system to identify these outlier hospitals and make sure they are not
Peter Breadon, Stephen Duckett
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Evaluation of ergonomics awareness and its lack of application on medical laboratory practitioners in tertiary hospitals in Jos, Plateau, Nigeria

open access: yesInternational Journal of Medicine and Health Development
Background: The study of how people interact with their work environment is known as ergonomics. Medical laboratory practitioners are exposed to work-related musculoskeletal disorders, resulting in a reduction in the quality of health care services ...
Bamidele O Olumide   +9 more
doaj   +1 more source

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