Results 111 to 120 of about 514,467 (364)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CONTRIBUTION OF HOSPITALS TO NORTH DAKOTA'S ECONOMY

open access: yes
Community hospital administrators in North Dakota were surveyed to determine the amount and type of expenditures made to North Dakota entities in 1997. Estimates of net revenues retained within the state were also solicited. Forty-two of the 44 community
Bangsund, Dean A., Leistritz, F. Larry
core  

Topeka State Hospital

open access: yes, 1877
"Authorized 1875. [Opened in 1879 for treatment and care of the mentally ill.] From 1876 to 1901, under control of the Board of Trustees for the Control of Charitable Institutions; from 1901 to 1905, by Board of Trustees of State Charities and ...
Topeka State Hospital
core  

Tribute to reviewers

open access: yesWorld Journal of Pediatric Surgery, 2021
Ademola Olusegun Talabi   +5 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Measuring and comparing the (in)efficiency of German and Swiss hospitals [PDF]

open access: yes
A nonparametric Data Envelopment Analysis (DEA) is performed on hospitals in the federal state of Saxony (Germany) and in Switzerland. This study is of interest from three points of view.
Dittrich, Gunnar   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Do Patients Bypass Rural Hospitals? Determinants of Inpatient Hospital Choice in Rural California [PDF]

open access: yes
Rural hospitals play a crucial role in providing healthcare to rural Americans, a vulnerable and underserved population; however, rural hospitals have faced threats to their financial viability and many have closed as a result.
José J Escarce, Kanika Kapur
core  

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