Results 101 to 110 of about 169,909,800 (296)

Constitutional Derogations of Human Rights in a State of Emergency – European Experiences in the Covid-19 Pandemic

open access: yesStrategos, 2022
In a state of emergency when the safety of citizens usually is seriously endangered, in state constitutions special powers are provided for the state bodies. These special powers are imposed by the need to successfully deal with the threats.
Biljana Karovska Andonovska
doaj  

Connecticut State Emergency Response Commission [web site] [Harvested on 2012: Aug. 10]

open access: yes, 2012
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed June 1, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Emergency Response Commission.

core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Starea excepțională instituită / declarată constituțional, condiție a măsurilor derogatorii privind drepturile omului [PDF]

open access: yesForum Juridic, 2020
Unlike human rights interferences, which constitute a restriction on human rights during normal periods, human rights derogations are severe and widespread restrictions in exceptional cases.
Corneliu-Liviu Popescu
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Prolonged emergency and derogation of human rights: Why the European Court should raise its immunity system

open access: yesGerman Law Journal, 2019
States of emergency pose the most significant challenges to the safeguarding of fundamental rights and civil liberties. Crises are generally characterized by a strengthening of the executive to the detriment of judicial authority and parliamentary ...
Triestino Mariniello
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

CFP: Excursions Journal: States of Emergence, States of Emergency

open access: yes, 2011
<strong> Call for Papers </strong> 'States of Emergence, States of Emergency' Deadline for articles: 15th August 2011 Benjamin's remarks on states of emergency have been fundamental to an understanding of political life which considers the roles played by threat, danger and fear in processes of political control.
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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