Results 101 to 110 of about 3,090,729 (363)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Based on the articulation between the idea of an enemy in criminal law and the analysis of the historical importance of racism in the structure of our society, we will analyse how we are facing a real genocide of the black population in Brazil today ...
Mariana Paganote Dornellas +1 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Homo Sacer in Beckett’s Waiting for Godot
Agamben’s concept of homo sacer may have Roman genesis but its modern and postmodern connotation is far more consequential. Since the present world is a cauldron of biopolitical activities, its effect on the general populace, especially after the Second
Md. Nurul Quayum, Masrufa Alam
doaj +1 more source
Frontiers’ violence: The interplay of state of exception, frontier habitus, and organized violence
C. Schetter, M. Müller-Koné
semanticscholar +1 more source
UK State Pension Reform in a Public Choice Framework [PDF]
Social security systems for old age have been explicitly studied in a public choice framework for over 30 years. They illustrate extremely well the problems of allocating economic resources through a system of voting.
Booth, P. M.
core
Breaking a monad-comonad symmetry between computational effects
Computational effects may often be interpreted in the Kleisli category of a monad or in the coKleisli category of a comonad. The duality between monads and comonads corresponds, in general, to a symmetry between construction and observation, for instance
Dumas, Jean-Guillaume +2 more
core +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Racial quotas in university vis-à-vis the state of exception
There is a close interconnection between Education and Bioethics, as explicitly stated by the Universal Declaration of Bioethics and Human Rights and by the Universal Declaration of Human Rights.
Dario Palhares +2 more
doaj +1 more source

