Results 51 to 60 of about 3,021,739 (277)

Breaking a monad-comonad symmetry between computational effects

, 2014
Computational effects may often be interpreted in the Kleisli category of a monad or in the coKleisli category of a comonad. The duality between monads and comonads corresponds, in general, to a symmetry between construction and observation, for instance
Dumas, Jean-Guillaume, Duval, Dominique, Reynaud, Jean-Claude   +2 more
core   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Le non-droit, l’état d’exception et l’incertitude juridique comme outils de domination politique

Astérion, 2018
This paper aims to confront two notions that have acquired a particular importance in contemporary reflections on the law: the notion of “un-law” (“Unrecht” or “non-droit”), that was constructed after the second WW in order to think about the specific ...
Marie Goupy
doaj   +1 more source

Simultaneous Metal-Insulator and Antiferromagnetic Transitions in Orthorhombic Perovskite Iridate Sr0.94Ir0.78O2.68 Single Crystals [PDF]

, 2016
The orthorhombic perovskite SrIrO3 is a semimetal, an intriguing exception in iridates where the strong spin-orbit interaction coupled with electron correlations tends to impose a novel insulating state.
Cao, G., Schlottmann, P., Terzic, J., Wan, X. G., Wang, D., Wang, Jinchen, Wang, Xiaoping, Ye, Feng, Yuan, S. J., Zheng, H.   +9 more
core   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Hierarchical confirmatory factor analysis of the flow state scale in exercise [PDF]

, 2000
In this study, we examined the factor structure and internal consistency of the Flow State Scale using responses of exercise participants.This self-report questionnaire consists of nine subscales designed to assess flow in sport and physical activity. It
Karageorghis, CI, Terry, PC, Vlachopoulos, SP   +2 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Questão fundiária: posse tradicional versus propriedade da terra entre Brasil e Cabo Verde

Ciências Sociais Unisinos, 2013
This paper intends to analyze the social processes which enabled the ascension of slaves descendants as land owners in post-colonial contexts. The debate raised intends to discuss the relations that produce truth discourses, in which the old leasers ...
Carolina dos Anjos de Borba
doaj  

Estado de excepción neoliberal y resistencia en el sureste de México

Antípoda: Revista de Antropología y Arqueología
In November 2021, the President of Mexico (2018-2024) declared that the priority megaprojects of the National Development Plan (Maya Train, Isthmus of Tehuantepec Interoceanic Corridor, Dos Bocas Refinery) fall within the realm of national security ...
Agustín R. Vázquez García, Aline Zárate Santiago   +1 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source