Results 131 to 140 of about 4,107,771 (287)

Environmental Law: A Reevaluation of Federal Pre-Emption and the Commerce Clause [PDF]

open access: yes, 1978
This Comment addresses how the concern of state and local governments to regain control over environmental regulation has resulted in a marked increase in conflicts with the commerce and supremacy clauses of the Constitution. Various tests have been used
Alonso, Mark J.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Flexible Rate Filing Insurance Rate Regulation as Alternative to Incentive Incompatibility in Prior-Approval [PDF]

open access: yes
Competition can be an effective regulator of rates in property-casualty insurance markets. While many states have moved to file-and-use or use-and-file provisions, some have adopted flexible rate-filing regulations (flex-rating) as a means of combining ...
Strauss, Jason
core   +1 more source

Decoding the Sphinx-Like Silence : State Residency, Petition Circulation, and the First Amendment [PDF]

open access: yes, 2018
State governments are the primary regulators of elections and ballot access in the United States. State statutes determine who is eligible to be on the ballot in each particular state, as well as who may assist these individuals by gathering petition ...
Partelow, Ryan A.
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Biocontrol Potential of Bacillus subtilis A3 Against Corn Stalk Rot and Its Impact on Root-Associated Microbial Communities

open access: yesAgronomy
Fusarium stalk rot (FSR), a devastating soil-borne disease caused by Fusarium species, severely threatens global maize production through yield losses and mycotoxin contamination.
Liming Wang   +6 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Assessment of Variation in State Regulation of Generic Drug and Interchangeable Biologic Substitutions.

open access: yesJAMA Intern Med, 2021
Sacks CA   +5 more
europepmc   +1 more source

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