Results 121 to 130 of about 4,138,957 (310)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Supplemental irrigation mitigates yield loss of maize through reducing canopy temperature under heat stress

Agricultural Water Management
Due to global warming, high temperature stress severely impacts maize growth and development, especially during the early filling stage. Supplemental irrigation is an effective measure to mitigate high temperature stress in maize. However, the underlying
Huajian Jian, Zhen Gao, Yingying Guo, Xinyan Xu, Xiaoyu Li, Meijia Yu, Guangzhou Liu, Dahong Bian, Yanhong Cui, Xiong Du   +9 more
doaj   +1 more source

Federal and State Regulation of Trade-Marks [PDF]

, 1949
Diggins, Bartholomew
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A novel chassis for high-quality recombinant protein expression: apoptosis pathway engineering via multi-gene knockout and efficacy improvement of CHO cells

Journal of Biological Engineering
Background Chinese hamster ovary (CHO) cells are pivotal in biopharmaceutical production, yet balancing high recombinant protein yield with cell survival remains challenging.
Youzhi Wu, Ying Cao, Zexuan Guo, Yanhua Ma, Xiaohui Zan, Xingjin Gu, Fan Zhang, Chunxia Chai, Rui Nui, Qiang Shang, Wei Wang   +10 more
doaj   +1 more source

Exogenous melatonin improves cotton yield under drought stress by enhancing root development and reducing root damage

Journal of Integrative Agriculture
The exogenous application of melatonin by the root drenching method is an effective way to improve crop drought resistance. However, the optimal concentration of melatonin by root drenching and the physiological mechanisms underlying melatonin-induced ...
Lingxiao Zhu, Hongchun Sun, Ranran Wang, Congcong Guo, Liantao Liu, Yongjiang Zhang, Ke Zhang, Zhiying Bai, Anchang Li, Jiehua Zhu, Cundong Li   +10 more
doaj   +1 more source

State Hospital Rate-Setting Revisited [PDF]

, 2009
Reviews the impact of seven states' past regulation of hospital payments on state hospital cost increases. Considers how methods and enforcement capacities influence the effectiveness of rate-setting as well as implications for national healthcare ...
Graham Atkinson
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Regulation and corporate corruption: new evidence from the telecom sector [PDF]

This paper examines how government regulation in developing countries affects the form of corruption between business customers and service providers in the telecom sector.
Berg, Sanford V, Jiang, Liangliang, Lin, Chen   +2 more
core   +1 more source

Foreword: The Place of Private Accrediting among the Instruments of Government [PDF]

, 1994
The Federal Government relies on private accreditation in lieu of direct public regulation, especially in the fields of health care and education.
Havighurst, Clark C.
core   +2 more sources