Results 101 to 110 of about 3,307,050 (303)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
, 2007 We have real cause for being proud of our past and the heritage it has given us ... We have a rich past ... along with this heritage we have had thrust upon us a deep responsibility, John S. Rice said in 1959.
Jordan, Brian Matthew
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Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Who Bears Responsibility for the Provision of Security: The State or You? [PDF]
When defining the absence of a threat as an economic good, it is necessary to define this good using the standard economic typology: is security a private, public, club or common good?
Hella Engerer, Olaf J. de Groot
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Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Social responsibility and social security: The foundation of caja de pensiones para la vejez y de ahorros [PDF]
The concept of Corporate Social Responsibility (CSR) is not new. Over the course of time, many entrepreneurs have created and developed companies, with a strong sense of ethical and social responsibility.
Argandoña, Antonio +2 more
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2. Establishment of the School [PDF]
, 1996 The formal establishment of the New York State School of Industrial and Labor relations grew out of the thoughtful and vigorous action of a unique group of practical politicians who firmly believed, as they stated in their first report, that “Though we ...
Konvitz, Milton R. +2 more
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Responsibility and the Big Society [PDF]
This paper focuses on the interplay between Conservative thought as evinced by the current Conservative Party leadership and the idea of responsibility, which is a central concern in the Big Society programme.
Antje Bednarek
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A critical review of the capability approach in Australian Indigenous policy [PDF]
, 2015 The capability approach has recently been used in Australian Indigenous policy formation. Of particular note is how it has been used in some instances to justify current paternalistic and directive policies for Indigenous Australians.
Elise Klein
core +1 more source