Results 61 to 70 of about 21,614,891 (313)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

TMS-evoked changes in brain-state dynamics quantified by using EEG data

Frontiers in Human Neuroscience, 2013
To improve our understanding of the combined transcranial magnetic stimulation (TMS) and electroencephalography (EEG) method in general, it is important to study how the dynamics of the TMS-modulated brain activity differs from the dynamics of ...
Tuomas eMutanen, Tuomas eMutanen, Jaakko O. Nieminen, Jaakko O. Nieminen, Risto J. Ilmoniemi, Risto J. Ilmoniemi   +5 more
doaj   +1 more source

New electronic state documents list - October 2023

, 2023
The monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository.
South Carolina State Library
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The Illusion of State in State-Space Models

CoRR
State-space models (SSMs) have emerged as a potential alternative architecture for building large language models (LLMs) compared to the previously ubiquitous transformer architecture. One theoretical weakness of transformers is that they cannot express certain kinds of sequential computation and state tracking (Merrill & Sabharwal, 2023), which ...
William Merrill, Jackson Petty, Ashish Sabharwal   +2 more
openaire   +4 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

CSPPNet: A Convolution and State-Space-Based Photovoltaic Panel Extraction Network Using Gaofen-2 High-Resolution Imagery

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
With the rapid development of photovoltaic (PV) industry, it is crucial to accurately identify PV panels using remote sensing data. However, the existing methods still face problems, such as difficulty in distinguishing PV panels from easily confused ...
Wenqing Liu, Hongtao Huo, Luyan Ji, Yongchao Zhao, Xiaowen Liu, Jialei Xie   +5 more
doaj   +1 more source

Dynamic Characteristic Optimization of Ball Screw Feed Drive in Machine Tool Based on Modal Extraction of State Space Model

IEEE Access, 2019
The accurate prediction and research about the dynamic characteristic of machine tool during the design process are essential to develop high-performance machines.
Yang Yong, Zhang Wei-Min, Zhu Qi-Xin, Jiang Quan-Sheng   +3 more
doaj   +1 more source

Single-Piece State-Space Behavioral Models for IC Output Buffers [PDF]

, 2007
In this paper enhancements of parametric behavioral models for the output buffers of digital ICs are explored. A model based on a single-piece structure, which offers improved accuracy in describing state transition events for arbitrary load conditions ...
Savi, Patrizia, Siviero, C., Maio, I. A., Canavero, F., Stievano, Igor Simone, Savi, P., C. Siviero, Siviero, Claudio, I. A. Maio, Maio, Ivano Adolfo, P. Savi, Canavero, Flavio, Stievano, I. S., I. S. Stievano, F. G. Canavero   +14 more
core   +1 more source