Results 81 to 90 of about 1,180,844 (267)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Track-before-detect algorithm for airborne radar system

The Journal of Engineering, 2019
This study considers the detection of dim target via track-before-detect (TBD) in airborne radar system. Dim target detection by TBD is well-studied while aircraft ego-motion is not taken into account.
Yaru Wang, Jinghe Wang, Ming Wen, Wei Yi, Lingjiang Kong   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Nonlinear Control of a Permanent Magnet Synchronous Motor Based on State Space Neural Network Model Identification and State Estimation by Using a Robust Unscented Kalman Filter

Eng
This work proposes a nonlinear modeling of a permanent magnet synchronous motor (PMSM) based on state space neural networks. The state space neural network is trained and the state variables (currents in a direct–quadrature frame and the rotational speed)
Sergio Velarde-Gomez, Eduardo Giraldo
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Load Frequency Optimal Active Disturbance Rejection Control of Hybrid Power System

Algorithms
The widespread adoption of the power grid has led to increased attention to load frequency control (LFC) in power systems. The LFC strategy of multi-source hybrid power systems, including hydroelectric generators, Wind Turbine Generators (WTGs), and ...
Kuansheng Zou, Yue Wang, Baowei Liu, Zhaojun Zhang   +3 more
doaj   +1 more source

Algebraic Frameworks for Measurement in the Natural Sciences

Measurement Science Review, 2012
The goals of this paper fall into three related areas: (i) we present an overview of a universal algebraic paradigm in which measurement specialists can construct formal models of measurement in a unified manner and systematically reason about a large ...
Domotor Zoltan
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Description of behavior of national economies in state space [PDF]

Acta Montanistica Slovaca, 2008
This paper deals with analysis of behavior of national economies by using the total least squares method. National economies are described in state space of the following variables: gross domestic product, inflation, and unemployment.
Ivo Petráš, Dagmar Bednárová, Igor Podlubný   +2 more
doaj