Results 71 to 80 of about 1,180,844 (267)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Frequency Response Analysis of State Space Models for Time Series Analysis

open access: yesEarth and Space Science
State space models are well‐suited for time series in which the evolution of variables cannot be well represented by deterministic basis functions. A key challenge in using state space models is the selection of the noise variance parameters.
Koen Haakman   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Development of Methods for Sensitivity Analysis of Electrical Energy Networks and Systems within State Space

open access: yesEnergies
This paper presents a new method that should make it possible to determine the sensitivity of uncontrolled electrical power grids with only a modest amount of effort.
Tobias Blenk, Christian Weindl
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Bye-bye, bye advantage: estimating the competitive impact of rest differential in the National Football League

open access: yesFrontiers in Behavioral Economics
The National Football League (NFL) sets its regular season schedule to optimize viewership and minimize competitive inequities. One inequity assumed to impact team performance is rest differential, defined as the relative number of days between games ...
Michael J. Lopez, Thompson Bliss
doaj   +1 more source

Assessing the Relationship between Market Factors and Regional Price Dynamics in U.S. Cattle Markets

open access: yesJournal of Agricultural and Resource Economics, 1997
Regional live cattle prices are decomposed into two components: (a) a trend common to all regional cattle price series and (b) regional deviations or price dynamics around that trend.
Allan M. Walburger, Kenneth A. Foster
doaj   +1 more source

Dynamic state space partitioning for external memory state space exploration

open access: yesScience of Computer Programming, 2013
We describe a dynamic partitioning scheme useable by explicit state space exploration techniques that divide the state space into partitions, such as many external memory and distributed model checking algorithms. The goal of the scheme is to reduce the number of transitions that link states belonging to different partitions, and thereby limit the ...
Sami Evangelista   +1 more
openaire   +1 more source

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