Results 51 to 60 of about 19,149,312 (300)

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim   +11 more
wiley   +1 more source

Bacteriophages and the immune system of the macroorganism

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2019
Due to the emergence of antibiotic-resistant strains of bacteria in recent years, the treatment and prevention of various infections with bacteriophages have again become an important area of research.
I. A. Ivanovа   +4 more
doaj   +1 more source

State Supervision of Probation

open access: yesJournal of the American Institute of Criminal Law and Criminology, 1918
A new method and a new spirit has been brought about in criminal jurisprudence by the development of the probation system. The method has been grafted upon an antiquated criminal court system, producing profound changes. Developing ideals of social service and social diagnosis have produced the probation method and are in turn developed and fostered by
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Rekonstruksi Pengawasan Negara terhadap BUMN dalam UU No. 1 Tahun 2025: Kritik atas Model Kelembagaan BPI Danantara

open access: yesZaaken
State supervision over State-Owned Enterprises (SOEs) in Indonesia has undergone significant transformation following the enactment of Law Number 1 of 2025, particularly through the establishment of the Daya Anagata Nusantara Investment Management ...
Julia Angelica Jasmine Margareta
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Technology Originality and Convergence Analysis in the Wind Power Field Using Patents

open access: yesEnergies, 2022
Currently, the world is moving rapidly toward carbon neutrality, and renewable energy technology is very important in carbon neutrality. Among various renewable energy technologies, wind power is attracting much attention due to its sustainability ...
Kyungwon Joo, Mina Lee, Gooyong Lee
doaj   +1 more source

Freedom of Contract Under State Supervision

open access: yesSSRN Electronic Journal, 2015
This study investigates the theoretical obstacles freedom of contract brings to an economy where state ownership is pervasive while the market is not sufficiently competitive such as China. Contrary to the arguments made by existing literatures that attributed all the conflicts of interest between state and private investors and related agency problems
openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

ON STATE CONTROL (SUPERVISION) OVER COMPLIANCE WITH LABOR LEGISLATION

open access: yesПравовое государство: теория и практика, 2022
The tasks performed by the state control (supervision) in the field of labor law relations focus on the protection of labor rights and freedoms of citizens. In modern states, including the Russian Federation, the regulation of state control (supervision)
ARSENTIEVA Nadezhda Anatolyevna   +1 more
doaj   +1 more source

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