Results 61 to 70 of about 19,149,312 (300)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Latent Reasoning with Supervised Thinking States
CoRRReasoning with a chain-of-thought (CoT) enables Large Language Models (LLMs) to solve complex tasks but incurs significant inference costs due to the generation of long rationales. We propose Thinking States, a method that performs reasoning {\em while} the input is processing.
Ido Amos +6 more
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
State Supervision of Local Assessments [PDF]
The ANNALS of the American Academy of Political and Social Science, 1921 n ...
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
IEEE AccessAccurate power load forecasting for large industrial users plays a crucial role in developing effective power consumption plans and energy-saving strategies. It also contributes to optimizing the operational efficiency of the power grid.
Zhaoguo Wang +4 more
doaj +1 more source
, 2008 Vor dem Hintergrund eines stress- und ressourcentheoretischen Modells wurde im Rahmen eines faktoriellen multivariaten varianzanalytischen Designs (N = 451) untersucht, ob bei TeilnehmerInnen von Supervision Verbesserungen bei wahrgenommenen ...
Eichert, Hans-Christoph
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Towards effective practice in offender supervision [PDF]
, 2009 This paper has been prepared principally for the Performance Improvement Strategy Group - a group convened by the Community Justice Division of the Scottish Government to advise and assist in the development of criminal justice social work services in ...
McNeill, Fergus +1 more
core +2 more sources
Shipin yu jixieObjectiveTo establish a rapid detection method for 81 illegal weight loss additives in tablet candy using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).MethodsSamples were ultrasonically extracted with 80% methanol-water ...
Li Hongli +6 more
doaj +1 more source