Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
Active Sensing of Static Friction Coefficient ^|^mu; for Controlling Grasping Force
Youji YAMADA +4 more
openalex +2 more sources
Importance of Type and Direction of Eyelid Sliding to Mimic Blinking In Vitro for Dry Eye Disease and Contact Lens Research. [PDF]
Chen Y +3 more
europepmc +1 more source
Hierarchical Artificial Muscle with Nonlinear Elasticity for Antagonistic and Cyclic Robotics
We construct hierarchical muscles by plying nylon fibers around a heating wire. The hierarchical muscle shows a J‐shaped passive curve, which shows benefit in antagonistic muscle pair and work accumulation mechanism. We also develop a computational, first‐principle model to understand the physics of both active actuation stroke and passive J‐curve ...
Samuel Tsai +15 more
wiley +1 more source
Role of friction on the formation of confined granular structures. [PDF]
Oliveira VPS +3 more
europepmc +1 more source
Diffusion–Model–Driven Discovery of Ferroelectrics for Photocurrent Applications
We developed a diffusion model–based generative AI and high‐throughput screening framework that accelerates the discovery of photovoltaic ferroelectrics. By coupling AI driven crystal generation with machine learning and DFT screening, we identified Ca3P2 and LiCdP as new ferroelectric materials exhibiting strong polarization, feasible switching ...
Byung Chul Yeo +3 more
wiley +1 more source
Decrease of Static Friction Coefficient with Interface Growth from Single to Multiasperity Contact
Liang Peng +3 more
openalex +2 more sources
Advanced preclinical testing of a design-optimized ceramic bearing for a cervical total disc replacement. [PDF]
Kölle L +6 more
europepmc +1 more source

