Results 141 to 150 of about 1,066,098 (345)
A Probabilistic Study Of Safety Criteria For Design [PDF]
, 1972 National Science Foundation Under Grant GK ...
Ang, A.H-S., Ellingwood, Bruce Russell
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Microgravity manipulator demonstration [PDF]
A test rig is being developed that will be used to demonstrate and evaluate approaches to limiting manipulator base reactions in microgravity environments.
Brush, Andrew S.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
BuildingsThe use of recycled materials and locally sourced alternative binders in 3D concrete printing (3DCP) has significant potential to reduce carbon emissions in concrete construction.
A. H. M. Javed Hossain Talukdar +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Scaling laws for light weight optics, studies of light weight mirrors mounting and dynamic mirror stress, and light weight mirror and mount designs [PDF]
Scaling laws for light-weight optical systems are examined. A cubic relationship between mirror diameter and weight has been suggested and used by many designers of optical systems as the best description for all light-weight mirrors.
Cho, Myung K. +3 more
core +1 more source
Static and transient dynamic analysis of two-axis flexure support structure
Journal of Physics: Conference SeriesAbstract This paper aims to investigate the flexure support structure in the fast steering mirror (FSM). Firstly, the 3D model of the flexure support structure is created. Then, we calculate its theoretical stiffness value and carry out the static analysis.
Yan Wang, Lizhong Zhang
openaire +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Pressure distributions and oil-flow patterns for a swept circulation-control wing [PDF]
Pressure distributions and photographs of oil flow patterns are presented for a circulation control wing. The model was an aspect ratio four semispan wing mounted on the side wall of the NASA Ames Transonic Wind Tunnel. The airfoil was a 20 percent thick
Keener, Earl R. +2 more
core +1 more source