Results 41 to 50 of about 2,840,980 (293)

Forced response of shrouded blades with a coupled static/dynamic approach [PDF]

open access: yes, 2011
A coupled static-dynamic method is proposed and applied to bladed disks with shrouds, in order to calculate the nonlinear forced response in presence of friction damping in the frequency domain.
Zucca, Stefano   +2 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Comparison of Friction in Sliding Mechanics Using Different Ligation Methods on Ceramic Bracket with Metal Slot and Epoxy Resin-Coated Stainless Steel Esthetic Wire: An in Vitro Study

open access: yesJournal of Indian Orthodontic Society, 2019
Introduction: The friction generated during orthodontic treatment seems of concern in terms of anchorage and treatment duration. Different ligation methods have been developed to reduce the friction as compared with regular elastic modules.
Hina Desai   +3 more
doaj   +1 more source

Friction between Archwire of Different Sizes, Cross Section, Alloy and Brackets Ligated with Different Brands of Low Friction Elastic Ligatures- An Invitro Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Friction in orthodontic treatment does exist and is thought to reduce the efficiency of orthodontic appliances during sliding mechanics.
Bhushan Patil   +7 more
doaj   +1 more source

Static friction scaling of physisorbed islands: the key is in the edge. [PDF]

open access: yesNanoscale, 2014
The static friction preventing the free sliding of nanosized rare gas solid islands physisorbed on incommensurate crystalline surfaces is not completely understood.
N. Varini   +5 more
semanticscholar   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Modeling Method Analysis of the Friction Torque for High Speed Spindle Bearing

open access: yesMATEC Web of Conferences, 2018
The friction torque inside the high-speed spindle bearing determines the performance of the friction, wear, heat, temperature rise and life of the bearing.
Li Songsheng   +4 more
doaj   +1 more source

Comparative Evaluation of Frictional forces between different Archwire-bracket Combinations

open access: yesOrthodontic Journal of Nepal, 2014
Introduction: During sliding mechanics, frictional resistance is an important counterforce to orthodontic tooth movement; whichmust be controlled to allow application of light continuous forces.
Vinit Singh   +3 more
doaj   +1 more source

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