Results 51 to 60 of about 2,840,980 (293)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Static and kinetic friction of rapeseed
Research in Agricultural Engineering, 2007 he present paper examines the static and kinetic coefficient of friction of rapeseed. The project utilized two methods of determination of coefficient of friction of rapeseed: according Eurocode 1 (kinetic) in direct shear test and (static) in model silo.
R. Rusinek, M. Molenda
doaj +1 more source
, 2017 Problems with uniqueness and high parametric sensitivity of the solution of equations of motion, encountered in the static friction regime, are addressed. Friction in joints of a multibody system with closed-loop kinematic chains is discussed.
M. Wojtyra
semanticscholar +1 more source
, 2020 In this study, static coefficients of friction for laminated veneer lumber on steel surfaces were determined experimentally. The focus was on the frictional behaviors at different pressure levels, which were studied in combination with other influencing ...
Habrová, Karolína +12 more
core +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Jixie qiangdu, 2023 A statistical model of static friction factor of joint surfaces was deduced, which was more in line with the actual situation and takes into account the interaction of asperities and the deformation of the substrate.
XU YongTai, ZHANG XueLiang, ZHAO HaiLu
doaj
The Static Frictional Behaviors of Rubber for Pipe-Laying Operation
Applied Sciences, 2017 Experimental research is carried out to reveal the static frictional behaviors of rubber pipe contact systems. This research is motivated by deep water pipe-laying operations where rubber blocks are used to clamp the pipe to supply sufficient static ...
Yong-Jie Zhou +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Jixie chuandong, 2005 In this paper,an experimental device for measuring the static coefficient of friction was designed.Experiments were performed with this device to measure the static coefficient of friction for three kinds of material（45steel,HT35-61,QT80-2） in the same ...
曹东海, 卢泽生
doaj
Evaluation and modeling of structural hysteresis
Nihon Kikai Gakkai ronbunshu, 2017 In order to clarify the mechanism of the vehicle body hysteresis affecting “rigidity feeling”, one of the driver's sensory evaluation in the driving test, the influence of friction acting on spot welding flanges on hysteresis, which is drawn by ...
Takeshi KAWACHI +2 more
doaj +1 more source