Results 61 to 70 of about 4,389,718 (268)

Dynamic functional connectivity analysis reveals transient states of dysconnectivity in schizophrenia

NeuroImage: Clinical, 2014
Schizophrenia is a psychotic disorder characterized by functional dysconnectivity or abnormal integration between distant brain regions. Recent functional imaging studies have implicated large-scale thalamo-cortical connectivity as being disrupted in ...
E. Damaraju, E.A. Allen, A. Belger, J.M. Ford, S. McEwen, D.H. Mathalon, B.A. Mueller, G.D. Pearlson, S.G. Potkin, A. Preda, J.A. Turner, J.G. Vaidya, T.G. van Erp, V.D. Calhoun   +13 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Static and dynamic brain functional connectivity patterns in patients with unilateral moderate-to-severe asymptomatic carotid stenosis

Frontiers in Aging Neuroscience
Background and purposeAsymptomatic carotid stenosis (ACS) is an independent risk factor for ischemic stroke and vascular cognitive impairment, affecting cognitive function across multiple domains.
Junjun Wang, Junjun Wang, Linfeng Song, Binlin Tian, Li Yang, Xiaoyu Gu, Xu Chen, Lei Gao, Lin Jiang   +8 more
doaj   +1 more source

Neuroplastic changes in resting-state functional connectivity after stroke rehabilitation

, 2017
Most neuroimaging research in stroke rehabilitation mainly focuses on the neural mechanisms underlying the natural history of post-stroke recovery. However, connectivity mapping from resting-state fMRI is well suited for different neurological conditions
Fan, Yang-teng; Wu, Ching-yi; Liu, Ho-ling; Lin, Keh-chung; Wai, Yau-yau; Chen, Yao-liang
core   +1 more source

Dynamic brain connectivity is a better predictor of PTSD than static connectivity [PDF]

, 2017
Using resting-state functional magnetic resonance imaging, we test the hypothesis that subjects with post-traumatic stress disorder (PTSD) are characterized by reduced temporal variability of brain connectivity compared to matched healthy controls ...
D Rangaprakash, Gopikrishna Deshpande, Hu, Xiaoping, Deshpande, Gopikrishna, Jia, Hao, Lingjiang Li, Hao Jia, Lanka, Pradyumna, Xiaoping Hu, Liu, Tianming, Changfeng Jin, Rangaprakash, D, Pradyumna Lanka, Jin, Changfeng, Li, Lingjiang, Tianming Liu   +15 more
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Alzheimer’s Disease Projection From Normal to Mild Dementia Reflected in Functional Network Connectivity: A Longitudinal Study

Frontiers in Neural Circuits, 2021
BackgroundAlzheimer’s disease (AD) is the most common age-related problem and progresses in different stages, including mild cognitive impairment (early stage), mild dementia (middle-stage), and severe dementia (late-stage). Recent studies showed changes
Mohammad S. E. Sendi, Mohammad S. E. Sendi, Mohammad S. E. Sendi, Elaheh Zendehrouh, Robyn L. Miller, Robyn L. Miller, Zening Fu, Yuhui Du, Yuhui Du, Jingyu Liu, Jingyu Liu, Elizabeth C. Mormino, Elizabeth C. Mormino, David H. Salat, David H. Salat, Vince D. Calhoun, Vince D. Calhoun, Vince D. Calhoun, Vince D. Calhoun   +18 more
doaj   +1 more source

Individual differences in white matter microstructure reflect variation in functional connectivity during action choice. [PDF]

, 2007
The relation between brain structure and function is of fundamental importance in neuroscience. Comparisons between behavioral and brain imaging measures suggest that variation in brain structure correlates with the presence of specific skills[1-3 ...
Sebastian, C, Johansen-Berg, H, O Shea, J, Boorman, ED, Rushworth, MFS   +4 more
core  

Temporal and spectral characteristics of dynamic functional connectivity between resting-state networks reveal information beyond static connectivity. [PDF]

, 2018
Estimation of functional connectivity (FC) has become an increasingly powerful tool for investigating healthy and abnormal brain function. Static connectivity, in particular, has played a large part in guiding conclusions from the majority of resting ...
Marina Vannucci, Hsiang J Yeh, Michele Guindani, Vankov, Emilian R., Sharon Chiang, Yeh, Hsiang J, Chiang, Sharon, Hsiang J. Yeh, Stern, John M., John M Stern, John M. Stern, Vannucci, Marina, Guindani, Michele, Stern, John M, Yeh, Hsiang J., Emilian R. Vankov, Haneef, Zulfi, Vankov, Emilian R, Emilian R Vankov, Zulfi Haneef   +19 more
core   +2 more sources

sj-docx-1-acr-10.1177_02841851221127271 - Supplemental material for Alterations of static and dynamic functional network connectivity in acute ischemic brainstem stroke

, 2022
Supplemental material, sj-docx-1-acr-10.1177_02841851221127271 for Alterations of static and dynamic functional network connectivity in acute ischemic brainstem stroke by Jian Zhang and Yi Chang in Acta ...
Yi Chang (541216), Jian Zhang (1682)
core   +1 more source