Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie +12 more
wiley +1 more source
Dynamic edge-caching through content popularity and crowd prediction for short video services. [PDF]
Niu S, Liu Y, Liao K, Zhang B, Zou G.
europepmc +1 more source
Performance–Complexity Trade‐Offs in Battery Lifetime Prediction with Task‐Aware Transformers
FAST‐BatPro integrates convolutional feature extraction, flash Attention, and sparse attention for efficient battery lifetime prediction. Using limited early‐cycle data across multiple chemistries and operating conditions, it achieves robust accuracy while reducing inference latency, computational cost, and energy consumption.
Jingyuan Zhao +9 more
wiley +1 more source
LLM-guided population-based reinforcement learning: A scalable methodology for adaptive hyperparameter optimization. [PDF]
Chowdhury MTA +5 more
europepmc +1 more source
ABSTRACT Methane's efficient catalytic removal is vital for sustainable development. Bimetallic catalysts, though promising for methane activation, pose a design challenge due to their complex compositional space. This work introduces an integrated framework that combines high‐throughput density functional theory (DFT) and interpretable machine ...
Mingzhang Pan +8 more
wiley +1 more source
In-Sensor-Memory Computing for Post-Von Neumann Intelligence: A Perspective. [PDF]
Tang H, Yu N, Min P, Guo R, Zhang G.
europepmc +1 more source
Ferroelectric Devices for In‐Memory and In‐Sensor Computing
Inspired by biological systems, in‐memory and in‐sensor computing overcome von Neumann bottlenecks. Ferroelectric devices can mimic synaptic functions and sense stimuli like light or force, therefore are ideal for these paradigms. This review introduces the ferroelectric devices applied for in‐memory and in‐sensor computing, covering their structures ...
Hong Fang +5 more
wiley +1 more source
Anatomy-guided visual prompt tuning for cross-modal breast cancer understanding. [PDF]
Zhao S +10 more
europepmc +1 more source
Functional reserve mitigates cognitive-motor dual-task costs in older adults: insights from age, cohort, and behavioural strategies. [PDF]
Zhou T +7 more
europepmc +1 more source
Why the same herb is not the same medicine: plant epigenetic and metabolic plasticity as a missing variable in Chinese medicine. [PDF]
Hyun TK.
europepmc +1 more source

