Results 101 to 110 of about 1,093,881 (295)

A demand-centered scheduling framework for shared supercomputing resources: modeling, metrics, and case insights

Scientific Reports
The exponential growth of artificial intelligence and data-intensive applications has led to a significant surge in demand for supercomputing resources.
Hyungwook Shim
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Dynamic task scheduling algorithm with task synchronization and energy savings in hard real-time systems

Tongxin xuebao, 2009
HDSA（hybrid dynamic scheduling algorithm） was proposeed,which slows down processor via voltage/frequency scaling,such that the real-time schedulability and task synchronization can be satisfied concurrently with as minimum as possible energy consumption ...
HAN Jian-jun1, WU Xiao-dong1, LI Qing-hua1, Abbas A.Essa3   +3 more
doaj   +2 more sources

Research on Task Priority Model and Algorithm for Satellite Scheduling Problem

IEEE Access, 2019
In satellite scheduling system, one of the most important issues is task scheduling. Most of the existing algorithms focused on the scenario of normal tasks with fixed priority and don’t consider emergency tasks.
Jian Wu, Jiawei Zhang, Jinghui Yang, Lining Xing   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

A classification of predictive-reactive project scheduling procedures. [PDF]

The vast majority of the project scheduling research efforts over the past several years have concentrated on the development of workable predictive baseline schedules, assuming complete information and a static and deterministic environment.
Herroelen, Willy, Van de Vonder, Stijn, Demeulemeester, Erik   +2 more
core  

Static vs. Dynamic List-Scheduling Performance Comparison

Acta Polytechnica, 2003
The problem of efficient task scheduling is one of the most important and most difficult issues in homogeneous computing environments. Finding an optimal solution for a scheduling problem is NP-complete.
T. Hagras, J. Janeček
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source