Results 61 to 70 of about 1,017,985 (351)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Investigation of propeller slipstream effects on lateral and directional static stability of transport aircraft

open access: yesEngineering Applications of Computational Fluid Mechanics, 2022
The aerodynamic characteristics of turboprop aircraft are greatly affected by the running propellers. In this paper, propeller slipstream effects on the static lateral-directional stability characteristics of a typical twin-engine turboprop aircraft with
Shuai Zhao   +4 more
doaj   +1 more source

A stable static Universe? [PDF]

open access: yes, 2004
Starting from the assumption that general relativity might be an emergent phenomenon showing up at low-energies from an underlying microscopic structure, we re-analyze the stability of a static closed Universe filled with radiation.
A. S. Eddington   +14 more
core   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Effect of stand segmentation on growth and development of Norway spruce stands

open access: yesJournal of Forest Science, 2009
Segmentation of stands by tracks is often the first phase of forest tending. However, a suitable track width is still discussed in forest practice in the Czech Republic.
J. Horák, J. Novák
doaj   +1 more source

Method of static stability dominant identification

open access: yesIET Generation, Transmission & Distribution, 2023
Two extreme cases of static stability are voltage stability and power angle stability. The general stability analysis only focuses on one of the voltage stability or power angle stability.
Zhen Hu   +5 more
doaj   +1 more source

Stability of the Einstein static universe in presence of vacuum energy

open access: yes, 2009
The Einstein static universe has played a central role in a number of emergent scenarios recently put forward to deal with the singular origin of the standard cosmological model.
R. C. Tolman   +2 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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