Results 31 to 40 of about 48,090 (222)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Traveling spiral wave chimeras in coupled oscillator systems: emergence, dynamics, and transitions
New Journal of Physics, 2023 Systems of coupled nonlinear oscillators often exhibit states of partial synchrony in which some of the oscillators oscillate coherently while the rest remain incoherent.
M Bataille-Gonzalez +3 more
doaj +1 more source
Авіаційно-космічна техніка та технологія, 2022 The choice of programs and control algorithms for ACS determines the possibility of implementation in the engine of the expectancy in the construction of thermodynamic and strength characteristics.
Serhii Tovkach
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
A Balanced-Partitioning Treemapping Method for Digital Hierarchical Dataset
Virtual Reality & Intelligent Hardware, 2022 Background: The problem of visualizing a hierarchical dataset is an important and useful technical in many real happened situations. Folder system, stock market, and other hierarchical related dataset can use this technical for better understanding the ...
Cong Feng, Ming Lun Gong, Oliver Deussen
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Kinematics and Statics Analysis of Single Drive Multi-mode Metamorphic Manipulators
Jixie chuandong, 2023 In order to achieve accurate grasping of the target object with fewer drives, a metamorphic manipulator with single drive and multi-mode is proposed by combining metamorphic principle with the kite-straight-line mechanism.
Chang Boyan +3 more
doaj
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Simulation on following Performance of High-Speed Railway In Situ Testing System
Advances in Mechanical Engineering, 2013 Subgrade bears both the weight of superstructures and the impacts of running trains. Its stability affects the line smoothness directly, but in situ testing method on it is inadequate. This paper presents a railway roadbed in situ testing device, the key
Fei-Long Zheng +2 more
doaj +1 more source