Results 41 to 50 of about 523 (263)

Application of Static Var Compensator in Songhe Coal Mine

Gong-kuang zidonghua, 2010
In order to solve problems that traditional stationary reactive var compensator only compensates power factor to some extent and cannot eliminate higher harmonic pollution of power network caused by soft starters of high power loads of coal mine, the ...
DONG Jun, CHEN Tia
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Balancing asymmetrical load using a static var compensator [PDF]

IEEE PES Innovative Smart Grid Technologies, Europe, 2014
Power electronic controllers are employed in the transmission and distribution levels of the power systems. In transmission level applications, Flexible AC Transmission System (FACTS) controllers, consist of shunt and series static compensators, are applied for power flow control, stability enhancement, voltage regulation and power oscillation damping.
Alsulami, Amar, Bongiorno, Massimo, Srivastava, Kailash, Reza, Muhammad   +3 more
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Iterative Method for Determining the Values of the Susceptances of a Balancing Capacitive Compensator

Energies, 2018
To increase the electrical power quality, in the last decades, an intense development in the last decades of high-performance equipment built as advanced power electronics applications, such as the compensators from Switching Power Converter category ...
Adrian Pană, Alexandru Băloi, Florin Molnar-Matei   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Optimal Power Flow Analysis Based on Hybrid Gradient-Based Optimizer with Moth–Flame Optimization Algorithm Considering Optimal Placement and Sizing of FACTS/Wind Power

Mathematics, 2022
Optimal power flow (OPF) is one of the most significant electric power network control and management issues. Adding unreliable and intermittent renewable energy sources to the electrical grid increase and complicates the OPF issue, which calls for using
Amal Amin Mohamed, Salah Kamel, Mohamed H. Hassan, Mohamed I. Mosaad, Mansour Aljohani   +4 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Application Research of Static Var Generator in Wind Power System

Gong-kuang zidonghua, 2012
The paper analyzed and compared dynamic response time and harmonic characteristics of thyristor controlled reactor type static var compensator and static var generator, and got a conclusion that static var generator has quicker dynamic response speed and
WANG Gang, ZHAO Li-jun, LI Jie, YU Ya-bing   +3 more
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