Results 51 to 60 of about 523 (263)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Measurement-Based Analysis of Static Var Compensator Effects in Industrial Rolling Mill Grids

open access: yesEnergies
Power quality is a continuous concern in industry, especially in steel mills operating with nonlinear, fluctuating, and unbalanced loads. This paper investigates the influence of a Static Var Compensator (SVC) on power quality parameters in a hot ...
Petru Ivascanu   +2 more
doaj   +1 more source

Smart control application in the oscillations using FACTS (STATCOM and SVC)

open access: yesTecnura, 2017
Context: Reducing the oscillations of the electrical power systems is an important task in order to maintain their stability. This paper presents a methodology for adjusting the parameters of a fuzzy oscillations controller with a Static Var Compensator (
Alfonso James Alzate Gomez   +2 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

IMPROVEMENT OF POWER AND VOLTAGE QUALITY IN POWER SYSTEM DISTRIBUTION USING FACTS (SVC & DSTATCOM)

open access: yesDiyala Journal of Engineering Sciences, 2015
Power quality is one of the important fields in the electrical power and distribution system. In order to reduce the power losses and improve voltage level in electrical power and distribution system, Flexible AC Transmission Systems (FACTS) devices ...
Ali Najim Abdullah
doaj  

Improving the Operation of Transmission Systems Based on Static Var Compensator

open access: yesElectricity
This study evaluates and compares centralized and distributed reactive power compensation strategies using Static Var Compensators (SVCs) to enhance the performance of a high-voltage transmission system in the Caribbean region of Colombia.
Kelly M. Berdugo Sarmiento   +4 more
doaj   +1 more source

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