Results 51 to 60 of about 369 (262)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

EVALUATION OF EFFECT OF REACTIVE POWER CONTROL STRATEGY BASED ON VOLTAGE TERMINAL OF GENERATORS ON LIMIT INDUCED BIFURCATION AND DYNAMIC VOLTAGE STABILITY MARGIN [PDF]

مجله مدل سازی در مهندسی, 2013
Reactive power limit of power system generators has a significant effect on the static voltage stability margin such as maximum load ability point and dynamic voltage stability margin such as HB, LIB and SNB.
M.H. Velayati, N. Amjady, I. Khajevandi
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Pigeon-inspired optimization for reactive power planning with multitype FACTS devices

Journal of Electrical Systems and Information Technology
In this present work, pigeon inspired optimization (PIO) technique was applied for the optimal coordination of multi-type FACTS devices with the different VAr sources already existed in a connected power network.
Biplab Bhattacharyya, Suraj Kumar Rajbhar   +1 more
doaj   +1 more source

SLIME MOULD ALGORITHM FOR PRACTICAL OPTIMAL POWER FLOW SOLUTIONS INCORPORATING STOCHASTIC WIND POWER AND STATIC VAR COMPENSATOR DEVICE

Electrical engineering & Electromechanics, 2020
Purpose. This paper proposes the application procedure of a new metaheuristic technique in a practical electrical power system to solve optimal power flow problems, this technique namely the slime mould algorithm (SMA) which is inspired by the swarming ...
Ramzi Kouadri, Linda Slimani, Tarek Bouktir   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

COORDINACION DE PSS Y SVC PARA MEJORAR LA ESTABILIDAD DINAMICA

Ingeniería, 2011
Este trabajo constituye un aporte para mejorar el amortiguamiento de las oscilaciones de baja frecuencia (OBF) que se encuentran en el ámbito de 0.1 a 0.7 Ha y que son conocidas como oscilaciones entre áreas.
Eddie Araya Padilla
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Coordinated Excitation and Static Var Compensator Control with Delayed Feedback Measurements in SGIB Power Systems

Energies, 2020
In this paper, we present a nonlinear coordinated excitation and static var compensator (SVC) control for regulating the output voltage and improving the transient stability of a synchronous generator infinite bus (SGIB) power system. In the first stage,
Haris E. Psillakis, Antonio T. Alexandridis   +1 more
doaj   +1 more source