Results 91 to 100 of about 223,681 (205)

The annual rate of coronary artery calcification with combination therapy with a PCSK9 inhibitor and a statin is lower than that with statin monotherapy

npj Aging and Mechanisms of Disease, 2018
Statins and/or PCSK9 inhibitors cause the regression of coronary atheroma and reduce clinical events. However, it currently remains unclear whether these drugs modulate coronary atheroma calcification in vivo.
Yuichi Ikegami, Ikuo Inoue, Kaiji Inoue, Yuichi Shinoda, Shinichiro Iida, Seiichi Goto, Takanari Nakano, Akira Shimada, Mitsuhiko Noda   +8 more
doaj   +1 more source

Influence of statin use on clinicopathological characteristics of localized prostate cancer and outcomes obtained after radical prostatectomy: a single center study [PDF]

, 2015
To assess the impact of statin use on biochemical recurrence (BCR) of prostate cancer after radical prostatectomy (RP)
Cattarino, Susanna, Comperat, Eva, Cussenot, Olivier, Drouin, Sarah J, Leon, Priscilla, Mozer, Pierre, Renard Penna, Raphaële, Rouprêt, Morgan, Seisen, Thomas   +8 more
core  

Statin Use and the Progression of Coronary Artery Calcification in CKD: Findings From the KNOW-CKD Study

Kidney International Reports
Introduction: Statin treatment can reduce the risk of cardiovascular disease (CVD). Paradoxically, previous studies have shown that the use of statin is associated with the progression coronary artery calcification (CAC), a well-known predictor of CVD ...
Jihyun Yang, Kyu-Beck Lee, Hyang Kim, Soo Wan Kim, Yeong Hoon Kim, Su Ah Sung, Jayoun Kim, Kook-Hwan Oh, Ji Yong Jung, Young Youl Hyun   +9 more
doaj   +1 more source

Assessing long-term effectiveness and cost-effectiveness of statin therapy in the UK: a modelling study using individual participant data sets

Health Technology Assessment
Background Cardiovascular disease has declined but remains a major disease burden across developed countries. Objective To assess the effectiveness and cost-effectiveness of statin therapy across United Kingdom population categories.
Borislava Mihaylova, Runguo Wu, Junwen Zhou, Claire Williams, Iryna Schlackow, Jonathan Emberson, Christina Reith, Anthony Keech, John Robson, Richard Parnell, Jane Armitage, Alastair Gray, John Simes, Colin Baigent   +13 more
doaj   +1 more source

Pharmacogenetic GWAS meta-analysis of LDL cholesterol response to statins [PDF]

, 2014
Cardiolog
Barnes, MR, Consortium, GIST, Deshmukh, HA, Hitman, G, Jukema, JW, Krauss, RM, Postmus, I, Psaty, BM, Tardif, JC, Trompet, S   +9 more
core  

Stopping Statins [PDF]

Circulation, 2004
openaire   +2 more sources

Effects of adjunctive eslicarbazepine acetate on serum lipids in patients with partial-onset seizures: Impact of concomitant statins and enzyme-inducing antiepileptic drugs. [PDF]

, 2018
PURPOSE: To evaluate the effects of eslicarbazepine acetate (ESL) on lipid metabolism and to determine whether reduced statin exposure during ESL therapy has clinical consequences. SUBJECTS AND METHODS: We conducted a post-hoc analysis of pooled data for
Ben-Menachem, Elinor, Blum, David, Carreño, Mar, da Silva, Patrício Soares, Gidal, Barry E., Grinnell, Todd, Li, Yan, Mintzer, Scott, Moreira, Joana, Rogin, Joanne B., Schwab, Matthias, Wechsler, Robert T.   +11 more
core   +1 more source

Improvement in Renal Function and Reduction in Serum Uric Acid with Intensive Statin Therapy in Older Patients: A Post Hoc Analysis of the SAGE Trial. [PDF]

, 2015
BackgroundImprovement in renal function and decreases in serum uric acid (SUA) have been reported following prolonged high-intensity statin (HMG-CoA reductase inhibitor) therapy.
Deedwania, Prakash C, Fayyad, Rana S, Laskey, Rachel E, Stone, Peter H, Wilson, Daniel J   +4 more
core  

Statin therapy [PDF]

Clinical Medicine, 2001
openaire   +2 more sources

Prescribing statins [PDF]

British Journal of Clinical Pharmacology, 2005
openaire   +1 more source